ABCG5 (ATP binding cassette subfamily G member 5) - Rat Genome Database

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Gene: ABCG5 (ATP binding cassette subfamily G member 5) Pan paniscus
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Symbol: ABCG5
Name: ATP binding cassette subfamily G member 5
RGD ID: 11902350
Description: ENCODES a protein that exhibits ATP binding (ortholog); ATP hydrolysis activity (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN cholesterol homeostasis (ortholog); response to ionizing radiation (ortholog); response to muscle activity (ortholog); ASSOCIATED WITH arteriosclerosis (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); atherosclerosis (ortholog); FOUND IN apical part of cell (inferred); apical plasma membrane (inferred); ATP-binding cassette (ABC) transporter complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette sub-family G member 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21282,585,350 - 82,613,204 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A82,589,317 - 82,617,174 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A43,896,188 - 43,922,756 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A44,745,183 - 44,771,012 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A44,745,183 - 44,771,012 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ABCG5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21282,585,350 - 82,613,204 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A82,589,317 - 82,617,174 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A43,896,188 - 43,922,756 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A44,745,183 - 44,771,012 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A44,745,183 - 44,771,012 (-)Ensemblpanpan1.1panPan2
ABCG5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38243,806,211 - 43,839,231 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl243,812,472 - 43,838,865 (-)EnsemblGRCh38hg38GRCh38
GRCh37244,039,611 - 44,065,978 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36243,893,115 - 43,919,462 (-)NCBINCBI36Build 36hg18NCBI36
Build 34243,951,261 - 43,977,609NCBI
Celera243,878,347 - 43,904,690 (-)NCBICelera
Cytogenetic Map2p21NCBI
HuRef243,776,307 - 43,802,654 (-)NCBIHuRef
CHM1_1243,969,007 - 43,995,357 (-)NCBICHM1_1
T2T-CHM13v2.0243,810,586 - 43,844,196 (-)NCBIT2T-CHM13v2.0
Abcg5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391784,965,602 - 84,990,439 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1784,965,662 - 84,990,439 (-)EnsemblGRCm39 Ensembl
GRCm381784,658,174 - 84,683,011 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1784,658,234 - 84,683,011 (-)EnsemblGRCm38mm10GRCm38
MGSCv371785,057,574 - 85,082,263 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361784,566,560 - 84,591,249 (-)NCBIMGSCv36mm8
Celera1789,024,999 - 89,050,375 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1755.02NCBI
Abcg5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8615,717,936 - 15,743,376 (+)NCBIGRCr8
mRatBN7.269,965,118 - 9,990,563 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl69,965,118 - 9,990,563 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx610,253,680 - 10,285,836 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0610,563,072 - 10,595,227 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0610,084,742 - 10,110,340 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.067,935,771 - 7,961,207 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl67,935,771 - 7,961,207 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.067,871,269 - 7,896,799 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,027,647 - 8,064,425 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.168,027,646 - 8,064,425 (-)NCBI
Celera69,686,706 - 9,712,114 (+)NCBICelera
Cytogenetic Map6q12NCBI
Abcg5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544110,964,858 - 10,986,967 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544110,964,588 - 10,987,771 (-)NCBIChiLan1.0ChiLan1.0
ABCG5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11046,261,747 - 46,300,084 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1046,271,772 - 46,299,773 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1046,123,805 - 46,173,246 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01047,140,680 - 47,190,102 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1047,151,472 - 47,178,440 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11046,849,037 - 46,898,531 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01047,138,987 - 47,188,120 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01047,322,375 - 47,371,811 (-)NCBIUU_Cfam_GSD_1.0
Abcg5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629236,665,097 - 36,688,553 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365088,093,804 - 8,116,877 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365088,093,804 - 8,117,467 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCG5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl396,616,246 - 96,656,889 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1396,616,304 - 96,656,893 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23102,776,822 - 102,782,661 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABCG5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11463,414,241 - 63,439,193 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1463,413,691 - 63,438,917 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604548,447,921 - 48,472,592 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcg5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473825,287,841 - 25,309,828 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473825,287,574 - 25,310,643 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003809123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000029822   ⟹   ENSPPAP00000007448
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A44,745,183 - 44,771,012 (-)Ensembl
RefSeq Acc Id: XM_003809123   ⟹   XP_003809171
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21282,585,350 - 82,613,204 (+)NCBI
NHGRI_mPanPan12A82,589,317 - 82,617,174 (+)NCBI
Mhudiblu_PPA_v02A43,896,188 - 43,922,756 (-)NCBI
PanPan1.12A44,745,183 - 44,771,012 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003809171 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000007448
  ENSPPAP00000007448.1
RefSeq Acc Id: XP_003809171   ⟸   XM_003809123
- UniProtKB: A0A2R8ZSC6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000007448   ⟸   ENSPPAT00000029822
Protein Domains
ABC transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026725 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029822.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC_2_trans UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/TrEMBL
  ABCG_dom UniProtKB/TrEMBL
  ABCG_transporters UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report pps:100992590 UniProtKB/TrEMBL
NCBI Gene ABCG5 ENTREZGENE
PANTHER ABC TRANSPORTER G FAMILY MEMBER 28 UniProtKB/TrEMBL
  ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 5 UniProtKB/TrEMBL
Pfam ABC2_membrane UniProtKB/TrEMBL
  ABC2_membrane_7 UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R8ZSC6 ENTREZGENE, UniProtKB/TrEMBL