Advanced Search (OLGA)

Gene: PCK2 (phosphoenolpyruvate carboxykinase 2, mitochondrial) Pan paniscus

Subscribe to Updates

Analyze

Symbol:

PCK2

Name:

phosphoenolpyruvate carboxykinase 2, mitochondrial

RGD ID:

11807602

Description:

ENCODES a protein that exhibits phosphoenolpyruvate carboxykinase (GTP) activity (ortholog); phosphoenolpyruvate carboxykinase activity (ortholog); INVOLVED IN cellular response to glucose stimulus (ortholog); cellular response to tumor necrosis factor (ortholog); gluconeogenesis (ortholog); PARTICIPATES IN gluconeogenesis pathway; ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); COVID-19 (ortholog); Endotoxemia (ortholog); FOUND IN cytosol (inferred); mitochondrial matrix (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

phosphoenolpyruvate carboxykinase [GTP], mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	25,450,239 - 25,460,233 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	24,666,731 - 24,676,725 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	4,872,276 - 4,882,118 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	22,996,813 - 23,006,775 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	22,996,813 - 23,006,775 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PCK2	Bonobo	COVID-19		ISO	PCK2 (Homo sapiens)	9068941	mRNA:increased expression:peripheral blood mononuclear cell (human)	RGD	PMID:32228226 and REF_RGD_ID:28912744
PCK2	Bonobo	Endotoxemia		ISO	Pck2 (Rattus norvegicus)	9068941	mRNA more ...	RGD	PMID:19268478 and REF_RGD_ID:10427879

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PCK2	Bonobo	Brain-Lung-Thyroid Syndrome		ISO	PCK2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Brain-lung-thyroid syndrome	ClinVar	PMID:25741868
PCK2	Bonobo	lysinuric protein intolerance		ISO	PCK2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Lysinuric protein intolerance	ClinVar	PMID:28492532
PCK2	Bonobo	Phosphoenolpyruvate Carboxykinase Deficiency, Mitochondrial		ISO	PCK2 (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:24033266 more ...
PCK2	Bonobo	retinitis pigmentosa 27		ISO	PCK2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Retinitis pigmentosa 27	ClinVar	PMID:25741868 and PMID:28492532
PCK2	Bonobo	Specific Granule Deficiency		ISO	PCK2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Specific granule deficiency	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PCK2	Bonobo	Experimental Liver Cirrhosis		ISO	PCK2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:25380136
PCK2	Bonobo	Hypoxia		ISO	PCK2 (Homo sapiens)	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:18258771

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PCK2	Bonobo	Phosphoenolpyruvate Carboxykinase Deficiency, Mitochondrial		ISO	PCK2 (Homo sapiens)	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PCK2	Bonobo	cellular response to dexamethasone stimulus	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	cellular response to glucose stimulus		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:19635791 and REF_RGD_ID:7242950
PCK2	Bonobo	cellular response to glucose stimulus	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	cellular response to insulin stimulus	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	cellular response to tumor necrosis factor		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:19268478 and REF_RGD_ID:10427879
PCK2	Bonobo	gluconeogenesis		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:11440903 more ...
PCK2	Bonobo	gluconeogenesis	involved_in	IEA	UniProtKB:Q8BH04 and ensembl:ENSMUSP00000153733	150520179		Ensembl	GO_REF:0000107
PCK2	Bonobo	gluconeogenesis	involved_in	IEA	UniPathway:UPA00138	150520179		UniProt	GO_REF:0000041
PCK2	Bonobo	gluconeogenesis	involved_in	IEA	InterPro:IPR008209 more ...	150520179		InterPro	GO_REF:0000002
PCK2	Bonobo	gluconeogenesis	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	glycerol biosynthetic process from pyruvate	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	hepatocyte differentiation	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	oxaloacetate metabolic process		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:6049928 and REF_RGD_ID:2302971
PCK2	Bonobo	oxaloacetate metabolic process	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	positive regulation of insulin secretion		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:19635791 and REF_RGD_ID:7242950
PCK2	Bonobo	propionate catabolic process	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	pyruvate biosynthetic process		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:19635791 and REF_RGD_ID:7242950
PCK2	Bonobo	response to dexamethasone		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:16570165 and REF_RGD_ID:1625508
PCK2	Bonobo	response to lipid	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	response to lipopolysaccharide		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:19268478 and REF_RGD_ID:10427879
PCK2	Bonobo	response to starvation	involved_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PCK2	Bonobo	cytosol	located_in	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	mitochondrial matrix	is_active_in	IEA	UniProtKB:Q8BH04 and ensembl:ENSMUSP00000153733	150520179		Ensembl	GO_REF:0000107
PCK2	Bonobo	mitochondrion	located_in	IEA	UniProtKB:A0A384MTT2 more ...	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PCK2	Bonobo	carboxy-lyase activity	enables	IEA	UniProtKB-KW:KW-0210	150520179		UniProt	GO_REF:0000043
PCK2	Bonobo	GTP binding	enables	IEA	InterPro:IPR008209	150520179		InterPro	GO_REF:0000002
PCK2	Bonobo	GTP binding	enables	IEA	UniProtKB-KW:KW-0342	150520179		UniProt	GO_REF:0000043
PCK2	Bonobo	lyase activity	enables	IEA	UniProtKB-KW:KW-0456	150520179		UniProt	GO_REF:0000043
PCK2	Bonobo	manganese ion binding	enables	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	manganese ion binding	enables	IEA	UniProtKB:Q16822 and ensembl:ENSP00000216780	150520179		Ensembl	GO_REF:0000107
PCK2	Bonobo	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
PCK2	Bonobo	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	150520179		UniProt	GO_REF:0000043
PCK2	Bonobo	phosphoenolpyruvate carboxykinase (GTP) activity		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:6049928 and REF_RGD_ID:2302971
PCK2	Bonobo	phosphoenolpyruvate carboxykinase (GTP) activity	enables	IEA	EC:4.1.1.32	150520179		UniProt	GO_REF:0000003
PCK2	Bonobo	phosphoenolpyruvate carboxykinase (GTP) activity	enables	IEA	InterPro:IPR018091	150520179		InterPro	GO_REF:0000002
PCK2	Bonobo	phosphoenolpyruvate carboxykinase (GTP) activity	enables	IEA	UniProtKB:Q16822 more ...	150520179		Ensembl	GO_REF:0000107
PCK2	Bonobo	phosphoenolpyruvate carboxykinase (GTP) activity	enables	IEA	ARBA:ARBA00028523	150520179		UniProt	GO_REF:0000117
PCK2	Bonobo	phosphoenolpyruvate carboxykinase (GTP) activity	enables	IEA	PANTHER:PTN002611285	150520179		TreeGrafter	GO_REF:0000118
PCK2	Bonobo	phosphoenolpyruvate carboxykinase activity		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:11440903 more ...
PCK2	Bonobo	phosphoenolpyruvate carboxykinase activity	enables	IEA	InterPro:IPR008209 more ...	150520179		InterPro	GO_REF:0000002
PCK2	Bonobo	protein binding	enables	ISO	UniProtKB:P84022	9068941	PMID:21988832	IntAct	PMID:21988832
PCK2	Bonobo	purine nucleotide binding	enables	IEA	InterPro:IPR008210 and InterPro:IPR013035	150520179		InterPro	GO_REF:0000002

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
PCK2	Bonobo	gluconeogenesis pathway		ISO	Pck2 (Rattus norvegicus)	9068941		RGD	PMID:11440903 more ...
PCK2	Bonobo	gluconeogenesis pathway		ISO	PCK2 (Homo sapiens)	9068941		RGD	PMID:18613815 and REF_RGD_ID:2302809

PMID:22301074	PMID:30032202

PCK2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	25,450,239 - 25,460,233 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	24,666,731 - 24,676,725 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	4,872,276 - 4,882,118 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	22,996,813 - 23,006,775 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	22,996,813 - 23,006,775 (+)	Ensembl	panpan1.1		panPan2

PCK2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	24,094,171 - 24,104,125 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	24,094,053 - 24,110,598 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	24,563,520 - 24,573,334 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	23,633,323 - 23,643,179 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	23,633,388 - 23,643,173	NCBI
Celera	14	4,427,958 - 4,437,809 (+)	NCBI		Celera
Cytogenetic Map	14	q11.2-q12	NCBI
HuRef	14	4,678,408 - 4,688,558 (+)	NCBI		HuRef
CHM1_1	14	24,562,148 - 24,571,997 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	18,292,333 - 18,302,437 (+)	NCBI		T2T-CHM13v2.0

Pck2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	55,777,721 - 55,787,477 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	55,777,723 - 55,788,699 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	55,540,263 - 55,550,020 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	55,540,266 - 55,551,242 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	56,159,103 - 56,168,854 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	54,494,337 - 54,504,088 (+)	NCBI		MGSCv36	mm8
Celera	14	53,345,110 - 53,354,861 (+)	NCBI		Celera
Cytogenetic Map	14	C3	NCBI
cM Map	14	28.19	NCBI

Pck2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	32,997,853 - 33,006,691 (+)	NCBI		GRCr8
mRatBN7.2	15	29,027,891 - 29,036,729 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	29,027,894 - 29,037,283 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	30,873,592 - 30,882,430 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	32,020,798 - 32,029,636 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	30,263,142 - 30,271,980 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	34,216,735 - 34,224,357 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	34,216,833 - 34,224,193 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	38,106,930 - 38,114,552 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	33,671,834 - 33,680,613 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	33,677,328 - 33,696,192 (+)	NCBI
Celera	15	28,603,811 - 28,612,649 (+)	NCBI		Celera
Cytogenetic Map	15	p13	NCBI

Pck2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	36,288,568 - 36,296,828 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	36,288,402 - 36,296,761 (-)	NCBI	ChiLan1.0	ChiLan1.0

PCK2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	4,099,016 - 4,107,870 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	4,098,671 - 4,107,865 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	4,020,846 - 4,030,924 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	4,209,738 - 4,219,816 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	4,209,258 - 4,220,128 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	3,900,384 - 3,910,462 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	3,962,137 - 3,972,205 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	4,224,247 - 4,234,326 (+)	NCBI		UU_Cfam_GSD_1.0

Pck2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	35,951,769 - 35,960,519 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936722	428,307 - 437,328 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936722	428,473 - 450,452 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PCK2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	75,187,197 - 75,197,733 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	75,187,195 - 75,197,613 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	80,458,494 - 80,468,914 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PCK2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	1,077,206 - 1,087,306 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	1,077,447 - 1,087,607 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666036	12,759,325 - 12,769,341 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pck2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624820	8,426,606 - 8,436,284 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624820	8,426,456 - 8,436,484 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_003809072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055097370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055097371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055097372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063596472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000044377 ⟹ ENSPPAP00000021574

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	14	22,996,813 - 23,006,775 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000044385 ⟹ ENSPPAP00000021582

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	14	23,000,983 - 23,006,611 (+)	Ensembl

RefSeq Acc Id:

XM_003809072 ⟹ XP_003809120

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	25,450,239 - 25,460,233 (+)	NCBI
NHGRI_mPanPan1	14	24,666,731 - 24,676,725 (+)	NCBI
Mhudiblu_PPA_v0	14	4,872,276 - 4,882,118 (+)	NCBI
PanPan1.1	14	22,996,813 - 23,006,775 (+)	NCBI

Sequence:

show sequence

TGGGTTTGGCGGTTGGGAGGCAGGGGTTGGGGCGGCGGCTGGGCTGACCTGGAGCCTGGAGCCCCGGGGCCGAGGGAGCTGGCCTGCCGGCGGGGAGGAGGAAAGCTAGTGCCAGCCCTACCAGGTTC
CGCCCCCGCGCCTGCCCCCCTCCTTTTTAAGCGCCTCCCGCCAACCTCTGCTGTGGCTCCCTTCGCCGCGCTCCCTCCTTCCCCGCCTTCCATACCTCCCCGGCTCCGCTCGGTTCCTGGCCACCCCG
CAGCCCCTGCCCAGGTGCCATGGCCGCATTGTACCGCCCTGGCCTGCGGCTTAGCTGGCATGGGCTGAGCCCCTTGGGCTGGCCATCATGCCGTAGCATCCAGACCCTGCGAGTGCTTAGTGGAGATC
TGGGCCAGCTTCCCACTGGCATTCGAGATTTTGTAGAGCACAGTGCCCGCCTGTGCCAACCAGAGGGCATCCACATCTGTGATGGAACTGAGGCTGAGAATACTGCCACACTGACCCTGCTGGAGCAG
CAGGGCCTCATCCGAAAGCTCCCCAAGTACAATAACTGCTGGCTGGCCCGCACAGACCCCAAGGATGTGGCACGAGTAGAGAGCAAGACGGTGATTGTAACTCCTTCTCAGCGGGACACGGTACCTCT
CCCGCCTGGTGGGGCCCGTGGGCAGCTGGGCAACTGGATGTCCCCAGCTGATTTCCAGCGAGCTGTGGATGAGAGGTTTCCAGGCTGCATGCAGGGCCGCACCATGTATGTGCTTCCATTCAGCATGG
GTCCTGTGGGCTCCCCGCTGTCCCGCATCGGGGTGCAGCTCACTGACTCAGCCTATGTGGTGGCAAGCATGCGTATTATGACCCGACTGGGGACACCTGTGCTTCAGGCCCTGGGAGATGGTGACTTT
GTCAAGTGTCTGCACTCCGTGGGCCAGCCCCTGACAGGACAAGGGGAGCCGGTGAGCAAGTGGCCGTGCAACCCAGAGAAAACCCTGATTGGCCATGTGCCCGACCAGCGGGAGATCATCTCCTTCGG
CAGCGGCTATGGTGGCAACTCCCTGCTGGGCAAGAAGTGCTTTGCCCTACGCATCGCCTCTCGGCTGGCCCGGGATGAGGGCTGGCTGGCAGAGCACATGCTGATCCTGGGCATCACCAGCCCTGCAG
GGAAGAAGCGCTATGTGGCAGCCGCCTTCCCTAGTGCCTGTGGCAAGACCAACCTGGCTATGATGCGGCCCGCACTGCCAGGCTGGAAAGTGGAGTGTGTAGGGGATGACATTGCTTGGATGAGGTTT
GACAGTGAAGGTCGACTCCGGGCCATCAACCCTGAGAACGGCTTCTTTGGGGTTGCCCCTGGTACCTCTGCCACCACCAATCCCAACGCCATGGCTACAATCCAGAGTAACACTATTTTTACCAATGT
GGCTGAGACCAGTGATGGTGGCGTGTACTGGGAGGGCATTGACCAGCCTCTTCCACCTGGTGTTACTGTGACCTCCTGGCTGGGCAAACCCTGGAAACCTGGTGACAAGGAGCCCTGTGCACATCCCA
ACTCTCGATTTTGTGCCCCGGCTCGCCAGTGCCCCATCATGGACCCAGCCTGGGAGGCCCCAGAGGGTGTCCCCATTGACGCCATCATCTTTGGTGGCCGCAGACCCAAAGGGGTACCCCTGGTATAC
GAGGCCTTCAACTGGCGTCATGGGGTGTTTGTGGGCAGCGCCATGCGCTCTGAGTCCACTGCTGCAGCAGAACACAAAGGGAAGATCATCATGCACGACCCATTTGCCATGCGGCCCTTTTTTGGCTA
CAACTTCGGGCACTACCTGGAACACTGGCTGAGCATGGAAGGGCGCAAGGGGGCCCAGCTGCCCCGTATCTTCCATGTCAACTGGTTCCGGCGTGACAAGGCAGGGCACTTCCTGTGGCCAGGCTTTG
GGGAGAATGCTCGGGTGCTAGACTGGATCTGCCGGCGGTTAGAGGGGGAGGACAGTGCCCGAGAGACACCCATTGGGCTGGTGCCAAAGGAAGGAGCCTTGGATCTCAGCGGCCTCGGAGCTATAGAC
ACCACTCAGCTGTTCTCCCTCCCCAAGGACTTCTGGGAACAGGAGGTTCGTGACATTCGGAGCTACCTGACAGAGCAGGTCAACCAGGATCTGCCTAAAGAGGTATTGGCTGAGCTTGAAGCCCTGGA
GAGACGTGTGCACAAAATGTGACCTGAGGCCCTAGTCTAGCAAGAGGACATAGCACCCTCATCTGGGAATAGGGAAGCCACCTTGCAGAAAATATGAGCAATTTGATATTAACTAACATCTTCAATGT
GCCATAGACCTTCCCACAAAGACTGTCCAATAATAAGAGATGCTTATCTATTTTACAC

hide sequence

RefSeq Acc Id:

XM_055097370 ⟹ XP_054953345

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	25,450,270 - 25,460,233 (+)	NCBI
NHGRI_mPanPan1	14	24,666,762 - 24,676,725 (+)	NCBI

RefSeq Acc Id:

XM_055097371 ⟹ XP_054953346

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	25,450,239 - 25,460,233 (+)	NCBI
NHGRI_mPanPan1	14	24,666,731 - 24,676,725 (+)	NCBI

RefSeq Acc Id:

XM_055097372 ⟹ XP_054953347

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	25,450,428 - 25,460,233 (+)	NCBI
NHGRI_mPanPan1	14	24,666,919 - 24,676,725 (+)	NCBI

RefSeq Acc Id:

XM_063596472 ⟹ XP_063452542

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	25,450,398 - 25,460,233 (+)	NCBI


Protein RefSeqs	XP_003809120	(Get FASTA)	NCBI Sequence Viewer
	XP_054953345	(Get FASTA)	NCBI Sequence Viewer
	XP_054953346	(Get FASTA)	NCBI Sequence Viewer
	XP_054953347	(Get FASTA)	NCBI Sequence Viewer
	XP_063452542	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000021574.1
	ENSPPAP00000021582.1

RefSeq Acc Id:	XP_003809120 ⟸ XM_003809072
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9AWJ1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAALYRPGLRLSWHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGIHICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTVPLPPGGAR GQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSKWPCNPEKTLIGHVPDQREIISFGSGYGGN SLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTIFTNVAETSDG GVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKIIMHDPFAMRPFFGYNFGHYL EHWLSMEGRKGAQLPRIFHVNWFRRDKAGHFLWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLGAIDTTQLFSLPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALERRVHKM hide sequence

Ensembl Acc Id:

ENSPPAP00000021574 ⟸ ENSPPAT00000044377

Ensembl Acc Id:

ENSPPAP00000021582 ⟸ ENSPPAT00000044385

RefSeq Acc Id:	XP_054953346 ⟸ XM_055097371
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9AWF3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054953345 ⟸ XM_055097370
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9AWF3 (UniProtKB/TrEMBL)

Protein Domains

Phosphoenolpyruvate carboxykinase C-terminal P-loop Phosphoenolpyruvate carboxykinase GTP-utilising N-

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000033979	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000044377.1	UniProtKB/TrEMBL
	ENSPPAT00000044385.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.449.10	UniProtKB/TrEMBL
	3.90.228.20	UniProtKB/TrEMBL
	Phosphoenolpyruvate Carboxykinase, domain 2	UniProtKB/TrEMBL
InterPro	PEP_carboxykin_GTP_CS	UniProtKB/TrEMBL
	PEP_carboxykinase_C	UniProtKB/TrEMBL
	PEP_carboxykinase_GTP	UniProtKB/TrEMBL
	PEP_carboxykinase_GTP_C	UniProtKB/TrEMBL
	PEP_carboxykinase_GTP_N	UniProtKB/TrEMBL
	PEP_carboxykinase_N	UniProtKB/TrEMBL
KEGG Report	pps:100973241	UniProtKB/TrEMBL
NCBI Gene	PCK2	ENTREZGENE
PANTHER	PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP], MITOCHONDRIAL	UniProtKB/TrEMBL
	PTHR11561	UniProtKB/TrEMBL
Pfam	PEPCK_GTP	UniProtKB/TrEMBL
	PEPCK_N	UniProtKB/TrEMBL
PIRSF	PEP_carboxykinase_GTP	UniProtKB/TrEMBL
PROSITE	PEPCK_GTP	UniProtKB/TrEMBL
Superfamily-SCOP	PEP carboxykinase-like	UniProtKB/TrEMBL
	SSF68923	UniProtKB/TrEMBL
UniProt	A0A2R9AWF3	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AWJ1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
		Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations