GJB2 (gap junction protein beta 2) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: GJB2 (gap junction protein beta 2) Pan paniscus
Analyze
Symbol: GJB2
Name: gap junction protein beta 2
RGD ID: 11806688
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); gap junction channel activity (ortholog); gap junction channel activity involved in cell communication by electrical coupling (ortholog); INVOLVED IN aging (ortholog); cell-cell signaling (ortholog); cellular response to dexamethasone stimulus (ortholog); ASSOCIATED WITH autoimmune thyroiditis (ortholog); autosomal dominant keratitis-ichthyosis-deafness syndrome (ortholog); autosomal dominant nonsyndromic deafness 3A (ortholog); FOUND IN astrocyte projection (ortholog); cell body (ortholog); cell junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11319,829,838 - 19,831,999 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1319,831,274 - 19,831,954 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0131,514,714 - 1,520,239 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
GJB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11319,829,838 - 19,831,999 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1319,831,274 - 19,831,954 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0131,514,714 - 1,520,239 (-)NCBIMhudiblu_PPA_v0panPan3
GJB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1320,187,463 - 20,192,938 (-)EnsemblGRCh38hg38GRCh38
GRCh381320,187,470 - 20,192,938 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371320,761,609 - 20,767,077 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361319,659,605 - 19,665,114 (-)NCBINCBI36hg18NCBI36
Build 341319,659,608 - 19,665,037NCBI
Celera131,823,407 - 1,828,919 (-)NCBI
Cytogenetic Map13q12.11NCBI
HuRef131,567,054 - 1,572,566 (-)NCBIHuRef
CHM1_11320,730,111 - 20,735,623 (-)NCBICHM1_1
Gjb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391457,336,059 - 57,342,159 (-)NCBIGRCm39mm39
GRCm39 Ensembl1457,336,057 - 57,342,159 (-)Ensembl
GRCm381457,098,602 - 57,104,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1457,098,600 - 57,104,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv371457,717,439 - 57,723,539 (-)NCBIGRCm37mm9NCBIm37
MGSCv361456,052,728 - 56,058,775 (-)NCBImm8
Celera1454,889,190 - 54,895,282 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1430.1NCBI
Gjb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21531,260,390 - 31,278,222 (-)NCBI
Rnor_6.0 Ensembl1537,377,316 - 37,383,277 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01537,377,313 - 37,394,494 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01541,224,497 - 41,236,203 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41536,153,526 - 36,159,490 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11536,169,226 - 36,175,190 (-)NCBI
Celera1530,972,813 - 30,978,777 (-)NCBICelera
Cytogenetic Map15p12NCBI
Gjb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955497988,422 - 989,099 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955497987,213 - 989,477 (-)NCBIChiLan1.0ChiLan1.0
GJB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2517,952,851 - 17,958,289 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12517,952,851 - 17,958,289 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gjb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367201,528,205 - 1,530,296 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GJB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.111774,090 - 781,252 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GJB2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.13801,786 - 808,165 (+)NCBI
ChlSab1.1 Ensembl3807,379 - 808,059 (+)Ensembl
Gjb2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477617,517,824 - 17,522,683 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003833007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000021512   ⟹   ENSPPAP00000004697
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1319,831,274 - 19,831,954 (-)Ensembl
RefSeq Acc Id: XM_003833007   ⟹   XP_003833055
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11319,829,838 - 19,831,999 (-)NCBI
Mhudiblu_PPA_v0131,514,714 - 1,520,239 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003833055 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003833055   ⟸   XM_003833007
- Sequence:
RefSeq Acc Id: ENSPPAP00000004697   ⟸   ENSPPAT00000021512
Protein Domains
CNX   Connexin_CCC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000019636 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000004697 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000021512 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1440.80 UniProtKB/TrEMBL
InterPro Connexin UniProtKB/TrEMBL
  Connexin26 UniProtKB/TrEMBL
  Connexin_CCC UniProtKB/TrEMBL
  Connexin_CS UniProtKB/TrEMBL
  Connexin_N UniProtKB/TrEMBL
  Connexin_N_sf UniProtKB/TrEMBL
KEGG Report pps:100970213 UniProtKB/TrEMBL
NCBI Gene GJB2 ENTREZGENE
PANTHER PTHR11984 UniProtKB/TrEMBL
Pfam Connexin UniProtKB/TrEMBL
PRINTS CONNEXIN UniProtKB/TrEMBL
  CONNEXINB2 UniProtKB/TrEMBL
PROSITE CONNEXINS_1 UniProtKB/TrEMBL
  CONNEXINS_2 UniProtKB/TrEMBL
SMART CNX UniProtKB/TrEMBL
  Connexin_CCC UniProtKB/TrEMBL
UniProt A0A2R8ZIA2_PANPA UniProtKB/TrEMBL