SEMA6A (semaphorin 6A) - Rat Genome Database

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Gene: SEMA6A (semaphorin 6A) Pan paniscus
Analyze
Symbol: SEMA6A
Name: semaphorin 6A
RGD ID: 11802954
Description: ENCODES a protein that exhibits identical protein binding (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); centrosome localization (ortholog); neuron migration (ortholog); ASSOCIATED WITH autistic disorder (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: semaphorin-6A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,683,864 - 111,815,906 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,837,525 - 109,969,536 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,793,272 - 111,924,937 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15117,589,267 - 117,721,127 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5117,592,313 - 117,651,098 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SEMA6A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,683,864 - 111,815,906 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,837,525 - 109,969,536 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,793,272 - 111,924,937 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15117,589,267 - 117,721,127 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5117,592,313 - 117,651,098 (-)Ensemblpanpan1.1panPan2
SEMA6A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385116,443,555 - 116,574,823 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5116,443,555 - 116,574,823 (-)EnsemblGRCh38hg38GRCh38
GRCh375115,779,251 - 115,910,519 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,807,150 - 115,938,450 (-)NCBINCBI36Build 36hg18NCBI36
Build 345115,807,150 - 115,938,398NCBI
Celera5111,728,814 - 111,860,108 (-)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5110,960,448 - 111,091,731 (-)NCBIHuRef
CHM1_15115,211,962 - 115,342,921 (-)NCBICHM1_1
T2T-CHM13v2.05116,956,014 - 117,086,961 (-)NCBIT2T-CHM13v2.0
Sema6a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391847,378,321 - 47,504,267 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1847,368,665 - 47,501,937 (-)EnsemblGRCm39 Ensembl
GRCm381847,245,254 - 47,371,200 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1847,235,598 - 47,368,870 (-)EnsemblGRCm38mm10GRCm38
MGSCv371847,404,908 - 47,528,522 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361847,370,585 - 47,494,199 (-)NCBIMGSCv36mm8
Celera1848,602,449 - 48,726,270 (-)NCBICelera
Cytogenetic Map18CNCBI
cM Map1825.08NCBI
Sema6a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81842,237,227 - 42,358,540 (-)NCBIGRCr8
mRatBN7.21840,050,623 - 40,171,954 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1840,050,624 - 40,171,954 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1842,083,839 - 42,205,156 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01842,785,785 - 42,907,144 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01840,578,873 - 40,700,244 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01841,330,519 - 41,451,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1841,333,551 - 41,389,510 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01840,972,328 - 41,092,331 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41841,545,350 - 41,665,721 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11841,582,877 - 41,703,796 (-)NCBI
Celera1838,297,774 - 38,419,108 (-)NCBICelera
Cytogenetic Map18q11NCBI
Sema6a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540836,217,588 - 36,307,284 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540836,219,814 - 36,344,131 (-)NCBIChiLan1.0ChiLan1.0
SEMA6A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1116,117,063 - 6,245,443 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl116,119,964 - 6,177,817 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha116,267,699 - 6,394,474 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0116,109,306 - 6,236,116 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl116,111,786 - 6,236,325 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1116,072,720 - 6,199,469 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0116,136,002 - 6,262,719 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0116,387,457 - 6,514,259 (-)NCBIUU_Cfam_GSD_1.0
Sema6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213128,900,607 - 129,024,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367421,599,723 - 1,661,013 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367421,599,725 - 1,726,084 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA6A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2120,560,099 - 120,687,106 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12120,560,095 - 120,687,597 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22125,466,636 - 125,593,422 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEMA6A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,740,553 - 19,870,790 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603458,528,236 - 58,661,402 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sema6a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247335,249,235 - 5,374,117 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247335,249,245 - 5,371,841 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000040429   ⟹   ENSPPAP00000017718
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5117,592,313 - 117,651,098 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040432   ⟹   ENSPPAP00000017721
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5117,592,313 - 117,651,098 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040434   ⟹   ENSPPAP00000017723
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5117,592,313 - 117,595,020 (-)Ensembl
RefSeq Acc Id: XM_003826715   ⟹   XP_003826763
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,683,864 - 111,815,894 (-)NCBI
NHGRI_mPanPan15109,837,525 - 109,969,345 (-)NCBI
Mhudiblu_PPA_v05111,793,272 - 111,924,921 (-)NCBI
PanPan1.15117,589,267 - 117,720,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952058   ⟹   XP_008950306
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,683,864 - 111,815,904 (-)NCBI
NHGRI_mPanPan15109,839,711 - 109,969,536 (-)NCBI
Mhudiblu_PPA_v05111,793,272 - 111,924,937 (-)NCBI
PanPan1.15117,589,267 - 117,721,127 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952060   ⟹   XP_008950308
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,683,864 - 111,815,902 (-)NCBI
NHGRI_mPanPan15109,837,525 - 109,969,535 (-)NCBI
Mhudiblu_PPA_v05111,793,272 - 111,924,935 (-)NCBI
PanPan1.15117,589,267 - 117,720,983 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952061   ⟹   XP_008950309
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,683,864 - 111,815,904 (-)NCBI
NHGRI_mPanPan15109,839,711 - 109,969,535 (-)NCBI
Mhudiblu_PPA_v05111,793,272 - 111,924,934 (-)NCBI
PanPan1.15117,589,267 - 117,721,126 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055112562   ⟹   XP_054968537
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,683,864 - 111,815,897 (-)NCBI
NHGRI_mPanPan15109,839,711 - 109,969,347 (-)NCBI
RefSeq Acc Id: XM_063604599   ⟹   XP_063460669
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,683,864 - 111,815,906 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008950306   ⟸   XM_008952058
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AK26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008950309   ⟸   XM_008952061
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AK26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003826763   ⟸   XM_003826715
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AK26 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008950308   ⟸   XM_008952060
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AKS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000017718   ⟸   ENSPPAT00000040429
RefSeq Acc Id: ENSPPAP00000017721   ⟸   ENSPPAT00000040432
RefSeq Acc Id: ENSPPAP00000017723   ⟸   ENSPPAT00000040434
RefSeq Acc Id: XP_054968537   ⟸   XM_055112562
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AK26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063460669   ⟸   XM_063604599
- Peptide Label: isoform X1
Protein Domains
Sema


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031930 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040429.1 UniProtKB/TrEMBL
  ENSPPAT00000040432.1 UniProtKB/TrEMBL
  ENSPPAT00000040434.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
InterPro Plexin_repeat UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Semaphorin UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene SEMA6A ENTREZGENE
PANTHER PTHR11036 UniProtKB/TrEMBL
  SEMAPHORIN-6A UniProtKB/TrEMBL
Pfam PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
PROSITE SEMA UniProtKB/TrEMBL
SMART PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  SSF101912 UniProtKB/TrEMBL
UniProt A0A2R9AK26 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AKS2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AKS7_PANPA UniProtKB/TrEMBL