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Gene: SEMA6A (semaphorin 6A) Homo sapiens
Symbol: SEMA6A
Name: semaphorin 6A
Description: Predicted to have chemorepellent activity and semaphorin receptor binding activity. Involved in cellular response to vascular endothelial growth factor stimulus; negative regulation of cell adhesion involved in sprouting angiogenesis; and negative regulation of signal transduction. Predicted to localize to the extracellular space and integral component of plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HT018; KIAA1368; SEMA; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; sema VIa; SEMA6A-1; SEMA6A1; semaphorin 6A-1; semaphorin VIA; semaphorin-6A; semaphorin-6A-1; SEMAQ; VIA
Mus musculus (house mouse) : Sema6a (sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sema6a (semaphorin 6A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema6a (semaphorin 6A)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA6A (semaphorin 6A)
Canis lupus familiaris (dog) : SEMA6A (semaphorin 6A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sema6a (semaphorin 6A)
Sus scrofa (pig) : SEMA6A (semaphorin 6A)
Chlorocebus sabaeus (green monkey) : SEMA6A (semaphorin 6A)
Heterocephalus glaber (naked mole-rat) : Sema6a (semaphorin 6A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl5116,443,616 - 116,574,934 (-)Ensembl
GRCh385116,443,555 - 116,574,823 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375115,779,251 - 115,910,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,807,150 - 115,938,450 (-)NCBINCBI36hg18NCBI36
Build 345115,807,150 - 115,938,398NCBI
Celera5111,728,814 - 111,860,108 (-)NCBI
Cytogenetic Map5q23.1NCBI
HuRef5110,960,448 - 111,091,731 (-)NCBIHuRef
CHM1_15115,211,962 - 115,342,992 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SEMA6A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313551
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.