SEMA7A (semaphorin 7A (JohnMiltonHagen blood group)) - Rat Genome Database

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Gene: SEMA7A (semaphorin 7A (JohnMiltonHagen blood group)) Pan paniscus
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Symbol: SEMA7A
Name: semaphorin 7A (JohnMiltonHagen blood group)
RGD ID: 11772160
Description: ENCODES a protein that exhibits chemorepellent activity (inferred); integrin binding (inferred); semaphorin receptor binding (inferred); INVOLVED IN axon extension (ortholog); neuron projection development (ortholog); olfactory lobe development (ortholog); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Bloom syndrome (ortholog); Brugada syndrome 8 (ortholog); FOUND IN GABA-ergic synapse (ortholog); presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: semaphorin 7A (John Milton Hagen blood group); semaphorin-7A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21663,636,920 - 63,665,516 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11567,800,514 - 67,825,191 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01553,351,662 - 53,376,327 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11572,972,475 - 72,996,987 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1572,972,475 - 72,996,953 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SEMA7A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21663,636,920 - 63,665,516 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11567,800,514 - 67,825,191 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01553,351,662 - 53,376,327 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11572,972,475 - 72,996,987 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1572,972,475 - 72,996,953 (-)Ensemblpanpan1.1panPan2
SEMA7A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381574,409,289 - 74,433,958 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1574,409,289 - 74,433,958 (-)EnsemblGRCh38hg38GRCh38
GRCh371574,701,630 - 74,726,299 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,489,376 - 72,513,329 (-)NCBINCBI36Build 36hg18NCBI36
Build 341572,489,375 - 72,513,329NCBI
Celera1551,648,857 - 51,673,527 (-)NCBICelera
Cytogenetic Map15q24.1NCBI
HuRef1551,497,440 - 51,522,110 (-)NCBIHuRef
CHM1_11574,819,752 - 74,844,421 (-)NCBICHM1_1
T2T-CHM13v2.01572,277,013 - 72,301,682 (-)NCBIT2T-CHM13v2.0
Sema7a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39957,846,879 - 57,870,148 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl957,847,395 - 57,870,148 (+)EnsemblGRCm39 Ensembl
GRCm38957,939,596 - 57,962,865 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl957,940,112 - 57,962,865 (+)EnsemblGRCm38mm10GRCm38
MGSCv37957,787,942 - 57,810,672 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36957,738,272 - 57,761,002 (+)NCBIMGSCv36mm8
Celera955,172,627 - 55,195,358 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.63NCBI
Sema7a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8867,244,318 - 67,267,060 (+)NCBIGRCr8
mRatBN7.2858,348,448 - 58,370,536 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl858,348,448 - 58,370,536 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx863,878,863 - 63,900,947 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0862,156,420 - 62,178,501 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0860,020,985 - 60,043,066 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0862,723,788 - 62,746,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl862,723,788 - 62,745,868 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0862,499,077 - 62,521,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,717,449 - 61,739,529 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1861,736,491 - 61,759,245 (+)NCBI
Celera857,812,746 - 57,834,816 (+)NCBICelera
Cytogenetic Map8q24NCBI
Sema7a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554503,401,777 - 3,423,363 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554503,401,732 - 3,424,547 (+)NCBIChiLan1.0ChiLan1.0
SEMA7A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13037,531,986 - 37,547,650 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3037,531,971 - 37,566,645 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3037,466,091 - 37,488,072 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03037,737,728 - 37,759,702 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3037,737,713 - 37,759,702 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13037,690,238 - 37,712,193 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03037,715,461 - 37,737,421 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03037,971,301 - 37,993,275 (-)NCBIUU_Cfam_GSD_1.0
Sema7a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640115,582,526 - 115,606,288 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647133,431,889 - 33,454,311 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647133,430,589 - 33,454,353 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA7A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl759,094,932 - 59,119,532 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1759,094,919 - 59,119,534 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SEMA7A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1269,039,774 - 9,063,700 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048132,564,014 - 132,588,657 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sema7a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624781221,812 - 248,185 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624781221,821 - 244,854 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000048789   ⟹   ENSPPAP00000025958
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1572,972,475 - 72,996,953 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000048791   ⟹   ENSPPAP00000025960
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1572,973,809 - 72,996,863 (-)Ensembl
RefSeq Acc Id: XM_003811109   ⟹   XP_003811157
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21663,636,920 - 63,665,516 (-)NCBI
NHGRI_mPanPan11567,800,514 - 67,825,191 (-)NCBI
Mhudiblu_PPA_v01553,351,662 - 53,376,327 (-)NCBI
PanPan1.11572,972,475 - 72,996,987 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034939131   ⟹   XP_034795022
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21663,636,920 - 63,661,327 (-)NCBI
NHGRI_mPanPan11567,800,514 - 67,824,920 (-)NCBI
Mhudiblu_PPA_v01553,351,662 - 53,376,063 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003811157 (Get FASTA)   NCBI Sequence Viewer  
  XP_034795022 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000025958.1
  ENSPPAP00000025960.1
RefSeq Acc Id: XP_003811157   ⟸   XM_003811109
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B8P0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034795022   ⟸   XM_034939131
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BG37 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000025958   ⟸   ENSPPAT00000048789
Ensembl Acc Id: ENSPPAP00000025960   ⟸   ENSPPAT00000048791
Protein Domains
Ig-like   Sema


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036098 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048789.1 UniProtKB/TrEMBL
  ENSPPAT00000048791.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema7A_sema UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Semaphorin UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene SEMA7A ENTREZGENE
PANTHER PTHR11036 UniProtKB/TrEMBL
  SEMAPHORIN-7A UniProtKB/TrEMBL
Pfam Ig_2 UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  SEMA UniProtKB/TrEMBL
SMART PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  SSF101912 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9B8P0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BG37 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-01-30 SEMA7A  semaphorin 7A (JohnMiltonHagen blood group)  SEMA7A  semaphorin 7A (John Milton Hagen blood group)  Symbol and/or name change 5135510 APPROVED