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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | RGD:1305192 | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SEMA7A mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | increases expression | ISO | RGD:1313075 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of SEMA7A mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1313075 | 6480464 | Ethinyl Estradiol results in increased expression of SEMA7A mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1313075 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SEMA7A mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of SEMA7A mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1313075 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SEMA7A mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1313075 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SEMA7A mRNA | CTD | PMID:24680724 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | RGD:1305192 | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,4-diaminotoluene | increases expression | ISO | RGD:1313075 | 6480464 | 2, 4-diaminotoluene results in increased expression of SEMA7A mRNA | CTD | PMID:20713471 | 2-hydroxypropanoic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of SEMA7A mRNA | CTD | PMID:30851411 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | RGD:1313075 | 6480464 | tetrabromobisphenol A results in increased expression of SEMA7A mRNA | CTD | PMID:25172293 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | RGD:1313075 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of SEMA7A mRNA | CTD | PMID:20188158 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of SEMA7A mRNA | CTD | PMID:28628672 | 3-methylcholanthrene | increases expression | ISO | RGD:1313075 | 6480464 | Methylcholanthrene results in increased expression of SEMA7A mRNA | CTD | PMID:20713471 | 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:1313075 | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of SEMA7A mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1313075 | 6480464 | bis4-hydroxyphenylsulfone results in increased expression of SEMA7A mRNA | CTD | PMID:30951980 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1313075 | 6480464 | Fenretinide results in increased expression of SEMA7A mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | ISO | RGD:1305192 | 6480464 | Propylthiouracil results in decreased expression of SEMA7A mRNA | CTD | PMID:24780913 more ... | acetamide | increases expression | ISO | RGD:1305192 | 6480464 | acetamide results in increased expression of SEMA7A mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of SEMA7A intron | CTD | PMID:30157460 | arsenous acid | decreases expression | EXP | | 6480464 | Arsenic Trioxide results in decreased expression of SEMA7A mRNA | CTD | PMID:20458559, PMID:27829220 | benzo[a]pyrene | increases expression | ISO | RGD:1313075 | 6480464 | Benzoapyrene results in increased expression of SEMA7A mRNA | CTD | PMID:21569818 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzoapyrene affects the methylation of SEMA7A promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | EXP | | 6480464 | 7 more ... | CTD | PMID:20382639 | benzo[b]fluoranthene | increases expression | ISO | RGD:1313075 | 6480464 | benzobfluoranthene results in increased expression of SEMA7A mRNA | CTD | PMID:26377693 | bisphenol A | affects expression | ISO | RGD:1305192 | 6480464 | bisphenol A affects the expression of SEMA7A mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | RGD:1305192 | 6480464 | bisphenol A results in increased expression of SEMA7A mRNA | CTD | PMID:30816183 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SEMA7A mRNA | CTD | PMID:29275510 | bisphenol F | increases expression | ISO | RGD:1313075 | 6480464 | bisphenol F results in increased expression of SEMA7A mRNA | CTD | PMID:30951980 | Brodifacoum | increases expression | ISO | RGD:1305192 | 6480464 | bromfenacoum results in increased expression of SEMA7A protein | CTD | PMID:28903499 | buta-1,3-diene | increases expression | ISO | RGD:1313075 | 6480464 | 1, 3-butadiene results in increased expression of SEMA7A mRNA | CTD | PMID:29038090 | butanal | increases expression | EXP | | 6480464 | butyraldehyde results in increased expression of SEMA7A mRNA | CTD | PMID:26079696 | C60 fullerene | decreases expression | ISO | RGD:1305192 | 6480464 | fullerene C60 results in decreased expression of SEMA7A mRNA | CTD | PMID:19167457 | carbon nanotube | increases expression | ISO | RGD:1313075 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chloroprene | increases expression | ISO | RGD:1313075 | 6480464 | Chloroprene results in increased expression of SEMA7A mRNA | CTD | PMID:23125180 | chlorpyrifos | decreases expression | ISO | RGD:1313075 | 6480464 | Chlorpyrifos results in decreased expression of SEMA7A mRNA | CTD | PMID:20350560 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of SEMA7A mRNA | CTD | PMID:27392435 | cocaine | affects expression | ISO | RGD:1305192 | 6480464 | Cocaine affects the expression of SEMA7A mRNA | CTD | PMID:15691709 | dexamethasone | decreases expression | ISO | RGD:1313075 | 6480464 | Dexamethasone results in decreased expression of SEMA7A mRNA | CTD | PMID:22733784 | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of SEMA7A mRNA | CTD | PMID:28628672 | diarsenic trioxide | decreases expression | EXP | | 6480464 | Arsenic Trioxide results in decreased expression of SEMA7A mRNA | CTD | PMID:20458559, PMID:27829220 | diazinon | increases methylation | EXP | | 6480464 | Diazinon results in increased methylation of SEMA7A gene | CTD | PMID:22964155 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of SEMA7A mRNA | CTD | PMID:29803840 | fluoranthene | decreases expression | ISO | RGD:1313075 | 6480464 | fluoranthene results in decreased expression of SEMA7A mRNA | CTD | PMID:28329830 | formaldehyde | decreases expression | EXP | | 6480464 | Formaldehyde results in decreased expression of SEMA7A mRNA | CTD | PMID:28937961 | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of SEMA7A mRNA | CTD | PMID:28628672 | leflunomide | decreases expression | EXP | | 6480464 | leflunomide results in decreased expression of SEMA7A mRNA | CTD | PMID:28988120 | methotrexate | increases expression | EXP | | 6480464 | Methotrexate results in increased expression of SEMA7A mRNA | CTD | PMID:21678067 | microcystin | increases expression | ISO | RGD:1305192 | 6480464 | Microcystins results in increased expression of SEMA7A protein | CTD | PMID:22430071 | naphthalene | increases expression | ISO | RGD:1313075 | 6480464 | naphthalene results in increased expression of SEMA7A mRNA | CTD | PMID:18978301 | nickel sulfate | decreases expression | EXP | | 6480464 | nickel sulfate results in decreased expression of SEMA7A mRNA | CTD | PMID:22714537 | ozone | increases expression | ISO | RGD:1305192 | 6480464 | Ozone results in increased expression of SEMA7A mRNA | CTD | PMID:28623178 | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromateVI results in decreased expression of SEMA7A mRNA | CTD | PMID:22714537 | potassium dichromate | decreases expression | EXP | | 6480464 | Potassium Dichromate results in decreased expression of SEMA7A protein | CTD | PMID:23718831 | rac-lactic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of SEMA7A mRNA | CTD | PMID:30851411 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide analog results in increased expression of SEMA7A mRNA | CTD | PMID:25895662 | sodium arsenate | affects methylation | ISO | RGD:1313075 | 6480464 | sodium arsenate affects the methylation of SEMA7A promoter | CTD | PMID:20667999 | sodium arsenate | increases expression | ISO | RGD:1313075 | 6480464 | sodium arsenate results in increased expression of SEMA7A mRNA | CTD | PMID:20667999 | succimer | multiple interactions | ISO | RGD:1313075 | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SEMA7A mRNA | CTD | PMID:21641980 | sulforaphane | decreases expression | EXP | | 6480464 | sulforafan results in decreased expression of SEMA7A mRNA | CTD | PMID:31838189 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of SEMA7A mRNA | CTD | PMID:31533062 | tetrachloromethane | multiple interactions | ISO | RGD:1305192 | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SEMA7A mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | RGD:1305192 | 6480464 | Carbon Tetrachloride results in increased expression of SEMA7A mRNA | CTD | PMID:31150632 | thyroxine | increases expression | ISO | RGD:1305192 | 6480464 | Thyroxine results in increased expression of SEMA7A mRNA | CTD | PMID:29901742 | titanium dioxide | increases expression | ISO | RGD:1313075 | 6480464 | titanium dioxide results in increased expression of SEMA7A mRNA | CTD | PMID:27760801 | triclosan | increases expression | EXP | | 6480464 | Triclosan results in increased expression of SEMA7A mRNA | CTD | PMID:30510588 | troglitazone | decreases expression | ISO | RGD:1313075 | 6480464 | troglitazone results in decreased expression of SEMA7A mRNA | CTD | PMID:28973697 | urethane | increases expression | EXP | | 6480464 | Urethane results in increased expression of SEMA7A mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of SEMA7A gene | CTD | PMID:29154799 | |