LOC100986398 (hydroxycarboxylic acid receptor 3) - Rat Genome Database

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Gene: LOC100986398 (hydroxycarboxylic acid receptor 3) Pan paniscus
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Symbol: LOC100986398 (Ensembl: HCAR3)
Name: hydroxycarboxylic acid receptor 3
RGD ID: 11767575
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); GTP binding (inferred); nicotinic acid receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); purinergic nucleotide receptor signaling pathway (inferred); ASSOCIATED WITH essential hypertension (ortholog); short chain acyl-CoA dehydrogenase deficiency (ortholog); Skin Neoplasms (ortholog); FOUND IN membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: HCAR3
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210130,808,252 - 130,814,753 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112130,804,391 - 130,811,129 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012120,318,905 - 120,322,068 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112124,553,121 - 124,555,252 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12124,553,940 - 124,555,103 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell junction  (IEA)
membrane  (IEA,ISO)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100986398
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210130,808,252 - 130,814,753 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112130,804,391 - 130,811,129 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012120,318,905 - 120,322,068 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112124,553,121 - 124,555,252 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12124,553,940 - 124,555,103 (-)Ensemblpanpan1.1panPan2
HCAR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812122,714,756 - 122,716,811 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12122,714,756 - 122,716,811 (-)EnsemblGRCh38hg38GRCh38
GRCh3712123,199,303 - 123,201,358 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612121,765,256 - 121,767,392 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412121,724,182 - 121,726,224NCBI
Celera12122,778,682 - 122,780,822 (-)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12120,159,744 - 120,161,468 (-)NCBIHuRef
CHM1_112123,167,514 - 123,169,650 (-)NCBICHM1_1
T2T-CHM13v2.012122,710,140 - 122,712,195 (-)NCBIT2T-CHM13v2.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000026468   ⟹   ENSPPAP00000005963
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl12124,553,940 - 124,555,103 (-)Ensembl
RefSeq Acc Id: XM_003812130   ⟹   XP_003812178
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210130,808,252 - 130,814,753 (-)NCBI
NHGRI_mPanPan112130,804,391 - 130,811,129 (-)NCBI
Mhudiblu_PPA_v012120,318,905 - 120,322,068 (-)NCBI
PanPan1.112124,553,121 - 124,555,252 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003812178 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein APT70331 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005963.1
RefSeq Acc Id: XP_003812178   ⟸   XM_003812130
- UniProtKB: A0A4Y1JWN7 (UniProtKB/TrEMBL),   A0A2R8ZLY5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000005963   ⟸   ENSPPAT00000026468
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000024039 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000026468.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  HCARs UniProtKB/TrEMBL
KEGG Report pps:100986398 UniProtKB/TrEMBL
NCBI Gene LOC100986398 ENTREZGENE
PANTHER HYDROXYCARBOXYLIC ACID RECEPTOR 2 UniProtKB/TrEMBL
  PTHR46048:SF5 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  P2YPURNOCPTR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A2R8ZLY5 ENTREZGENE, UniProtKB/TrEMBL
  A0A4Y1JWN7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-25 LOC100986398  hydroxycarboxylic acid receptor 3  HCAR3  hydroxycarboxylic acid receptor 3  Symbol and/or name change 5135510 APPROVED
2020-07-01 HCAR3  hydroxycarboxylic acid receptor 3  LOC100986398  hydroxycarboxylic acid receptor 3  Symbol and/or name change 5135510 APPROVED