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Gene: Hcar2 (hydroxycarboxylic acid receptor 2) Mus musculus
Symbol: Hcar2
Name: hydroxycarboxylic acid receptor 2
Description: Exhibits G protein-coupled receptor activity; GTP binding activity; and purinergic nucleotide receptor activity. Involved in G protein-coupled receptor signaling pathway. Localizes to integral component of membrane. Is expressed in embryo. Orthologous to several human genes including HCAR3 (hydroxycarboxylic acid receptor 3); INTERACTS WITH 1,2-dimethylhydrazine; 3',5'-cyclic AMP; 4-hydroxynon-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G protein-coupled receptor 109A; G protein-coupled receptor 109B; G-protein coupled receptor 109; G-protein coupled receptor 109A; G-protein coupled receptor HM74; Gpr109a; Gpr109b; HM74; interferon-gamma inducible gene, Puma-g; mHM74b; niacin receptor 1; Niacr1; nicotinic acid receptor; PUMA-G; Pumag; putative seven transmembrane spanning receptor
Homo sapiens (human) : HCAR3 (hydroxycarboxylic acid receptor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hcar2 (hydroxycarboxylic acid receptor 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HCAR3 (hydroxycarboxylic acid receptor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl5123,863,570 - 123,865,499 (-)EnsemblGRCm38mm10GRCm38
GRCm385123,863,570 - 123,865,516 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375124,313,581 - 124,315,518 (-)NCBIGRCm37mm9NCBIm37
MGSCv365124,124,193 - 124,126,114 (-)NCBImm8
Celera5120,935,826 - 120,937,763 (-)NCBICelera
Cytogenetic Map5FNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Hcar2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553470
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.