TATDN1 (TatD DNase domain containing 1) - Rat Genome Database

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Gene: TATDN1 (TatD DNase domain containing 1) Pan paniscus
Analyze
Symbol: TATDN1
Name: TatD DNase domain containing 1
RGD ID: 11764390
Description: ENCODES a protein that exhibits 3'-5'-DNA exonuclease activity (inferred); hydrolase activity, acting on ester bonds (inferred); metal ion binding (inferred); INVOLVED IN DNA metabolic process (inferred); ASSOCIATED WITH hepatocellular carcinoma (ortholog); trichorhinophalangeal syndrome type I (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: deoxyribonuclease TATDN1; putative deoxyribonuclease TATDN1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27141,909,537 - 141,960,772 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18117,420,698 - 117,471,941 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08121,172,652 - 121,223,898 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18123,925,580 - 123,975,908 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8123,925,580 - 123,975,908 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
mitochondrion  (ISO)
nucleoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TATDN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27141,909,537 - 141,960,772 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18117,420,698 - 117,471,941 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08121,172,652 - 121,223,898 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18123,925,580 - 123,975,908 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8123,925,580 - 123,975,908 (-)Ensemblpanpan1.1panPan2
TATDN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388124,488,494 - 124,539,088 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8124,488,485 - 124,539,458 (-)EnsemblGRCh38hg38GRCh38
GRCh378125,500,735 - 125,551,329 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368125,569,930 - 125,620,492 (-)NCBINCBI36Build 36hg18NCBI36
Build 348125,569,931 - 125,620,492NCBI
Celera8121,688,850 - 121,739,446 (-)NCBICelera
Cytogenetic Map8q24.13NCBI
HuRef8120,826,460 - 120,876,799 (-)NCBIHuRef
CHM1_18125,540,989 - 125,591,573 (-)NCBICHM1_1
T2T-CHM13v2.08125,621,522 - 125,672,104 (-)NCBIT2T-CHM13v2.0
Tatdn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391558,762,002 - 58,805,605 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1558,762,004 - 58,805,587 (-)EnsemblGRCm39 Ensembl
GRCm381558,890,153 - 58,933,756 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1558,890,155 - 58,933,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv371558,721,708 - 58,765,285 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361558,720,236 - 58,763,813 (-)NCBIMGSCv36mm8
Celera1560,419,367 - 60,463,522 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1525.09NCBI
Tatdn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8792,339,452 - 92,370,445 (-)NCBIGRCr8
mRatBN7.2790,449,979 - 90,481,000 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl790,441,079 - 90,481,133 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx792,339,624 - 92,370,549 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0794,540,780 - 94,571,705 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0794,368,038 - 94,398,972 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0798,782,164 - 98,813,001 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl798,782,178 - 98,804,499 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0799,382,591 - 99,411,479 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4795,661,777 - 95,688,070 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera787,216,376 - 87,246,291 (-)NCBICelera
Cytogenetic Map7q33NCBI
Tatdn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555403,157,902 - 3,198,064 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555403,154,273 - 3,198,140 (-)NCBIChiLan1.0ChiLan1.0
TATDN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11322,561,003 - 22,624,891 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1322,573,150 - 22,624,987 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1322,526,573 - 22,590,366 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01322,902,967 - 22,966,810 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1322,915,023 - 22,966,909 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11322,623,357 - 22,687,633 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01322,733,160 - 22,797,184 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01322,976,000 - 23,040,061 (-)NCBIUU_Cfam_GSD_1.0
Tatdn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530315,697,525 - 15,730,665 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647023,123,730 - 23,167,274 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647023,123,693 - 23,156,764 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TATDN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl415,113,312 - 15,159,498 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1415,113,318 - 15,159,501 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2415,769,867 - 15,816,058 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TATDN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18119,055,356 - 119,103,328 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8119,052,415 - 119,102,839 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603921,082,891 - 21,130,886 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tatdn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473530,667,293 - 30,714,863 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000041303   ⟹   ENSPPAP00000018570
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8123,925,580 - 123,975,908 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000041314   ⟹   ENSPPAP00000018581
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8123,925,580 - 123,975,896 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000041327   ⟹   ENSPPAP00000018594
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8123,925,666 - 123,960,294 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000041335   ⟹   ENSPPAP00000018602
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8123,925,666 - 123,959,138 (-)Ensembl
RefSeq Acc Id: XM_003820465   ⟹   XP_003820513
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27141,909,537 - 141,960,770 (-)NCBI
NHGRI_mPanPan18117,420,698 - 117,471,939 (-)NCBI
Mhudiblu_PPA_v08121,172,652 - 121,223,896 (-)NCBI
PanPan1.18123,925,580 - 123,975,908 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003820466   ⟹   XP_003820514
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27141,909,537 - 141,960,772 (-)NCBI
NHGRI_mPanPan18117,420,698 - 117,471,941 (-)NCBI
Mhudiblu_PPA_v08121,172,652 - 121,223,898 (-)NCBI
PanPan1.18123,925,580 - 123,975,896 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034966575   ⟹   XP_034822466
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27141,909,537 - 141,960,092 (-)NCBI
NHGRI_mPanPan18117,420,698 - 117,471,264 (-)NCBI
Mhudiblu_PPA_v08121,172,656 - 121,223,217 (-)NCBI
RefSeq Acc Id: XM_034966576   ⟹   XP_034822467
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27141,909,537 - 141,960,707 (-)NCBI
NHGRI_mPanPan18117,420,698 - 117,471,879 (-)NCBI
Mhudiblu_PPA_v08121,172,656 - 121,223,840 (-)NCBI
RefSeq Acc Id: XM_063606891   ⟹   XP_063462961
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27141,909,537 - 141,939,788 (-)NCBI
RefSeq Acc Id: XP_003820513   ⟸   XM_003820465
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AS25 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003820514   ⟸   XM_003820466
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AMK9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034822467   ⟸   XM_034966576
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AMK9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034822466   ⟸   XM_034966575
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AMK9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000018570   ⟸   ENSPPAT00000041303
Ensembl Acc Id: ENSPPAP00000018581   ⟸   ENSPPAT00000041314
Ensembl Acc Id: ENSPPAP00000018594   ⟸   ENSPPAT00000041327
Ensembl Acc Id: ENSPPAP00000018602   ⟸   ENSPPAT00000041335
RefSeq Acc Id: XP_063462961   ⟸   XM_063606891
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AMM4 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032418 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000041303.1 UniProtKB/TrEMBL
  ENSPPAT00000041314.1 UniProtKB/TrEMBL
  ENSPPAT00000041327.1 UniProtKB/TrEMBL
  ENSPPAT00000041335.1 UniProtKB/TrEMBL
Gene3D-CATH Metal-dependent hydrolases UniProtKB/TrEMBL
InterPro DNase_TatD-rel_CS UniProtKB/TrEMBL
  Metal_Hydrolase UniProtKB/TrEMBL
  TatD-type_Hydrolase UniProtKB/TrEMBL
  TatD_family UniProtKB/TrEMBL
KEGG Report pps:100978389 UniProtKB/TrEMBL
NCBI Gene TATDN1 ENTREZGENE
PANTHER DEOXYRIBONUCLEASE TATDN1-RELATED UniProtKB/TrEMBL
  TATD FAMILY DEOXYRIBONUCLEASE UniProtKB/TrEMBL
Pfam TatD_DNase UniProtKB/TrEMBL
PIRSF DNase_TatD UniProtKB/TrEMBL
PROSITE TATD_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF51556 UniProtKB/TrEMBL
UniProt A0A2R9AMK9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AMM4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AS25 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AUJ8_PANPA UniProtKB/TrEMBL