MAP2K5 (mitogen-activated protein kinase kinase 5)

Advanced Search (OLGA)

Gene: MAP2K5 (mitogen-activated protein kinase kinase 5) Pan paniscus

Analyze

Symbol:

MAP2K5

Name:

mitogen-activated protein kinase kinase 5

RGD ID:

11750484

Description:

ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to growth factor stimulus (ortholog); ERK5 cascade (ortholog); heart development (ortholog); PARTICIPATES IN altered Erk5 MAPK signaling pathway; Erk5 MAPK signaling pathway; ASSOCIATED WITH amphetamine abuse (ortholog); Bloom syndrome (ortholog); Body Weight (ortholog); FOUND IN spindle (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

dual specificity mitogen-activated protein kinase kinase 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	56,797,445 - 57,064,491 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	60,970,950 - 61,238,196 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	46,493,139 - 46,760,271 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	64,761,465 - 65,029,655 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	64,761,394 - 65,029,655 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amphetamine abuse (ISO)

Bloom syndrome (ISO)

Body Weight (ISO)

Cardiomegaly (ISO)

colorectal cancer (ISO)

dilated cardiomyopathy (ISO)

neuronal ceroid lipofuscinosis (ISO)

prostate cancer (ISO)

Prostatic Neoplasms (ISO)

Sudden Death (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to growth factor stimulus (ISO)

ERK5 cascade (ISO)

heart development (IEA,ISO)

insulin-like growth factor receptor signaling pathway (IEA)

MAPK cascade (IEA,ISO)

negative regulation of canonical NF-kappaB signal transduction (ISO)

negative regulation of cell migration involved in sprouting angiogenesis (ISO)

negative regulation of chemokine (C-X-C motif) ligand 2 production (ISO)

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (ISO)

negative regulation of heterotypic cell-cell adhesion (ISO)

negative regulation of interleukin-8 production (ISO)

negative regulation of response to cytokine stimulus (ISO)

negative regulation of smooth muscle cell apoptotic process (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

positive regulation of cell growth (ISO)

positive regulation of epithelial cell proliferation (ISO)

positive regulation of protein metabolic process (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

protein phosphorylation (ISO)

Cellular Component

spindle (IEA)

Molecular Function

ATP binding (IEA,ISO)

MAP kinase kinase activity (IEA)

protein binding (ISO)

protein kinase activity (IEA,ISO)

protein serine/threonine kinase activity (IEA)

protein tyrosine kinase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

altered Erk5 MAPK signaling pathway (ISO)

Erk5 MAPK signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

MAP2K5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	56,797,445 - 57,064,491 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	60,970,950 - 61,238,196 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	46,493,139 - 46,760,271 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	64,761,465 - 65,029,655 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	64,761,394 - 65,029,655 (+)	Ensembl	panpan1.1		panPan2

MAP2K5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	67,542,703 - 67,807,114 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	67,542,703 - 67,807,117 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	67,835,041 - 68,099,452 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	65,622,075 - 65,886,506 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	65,719,944 - 65,886,505	NCBI
Celera	15	44,722,555 - 44,987,508 (+)	NCBI		Celera
Cytogenetic Map	15	q23	NCBI
HuRef	15	44,669,592 - 44,933,408 (+)	NCBI		HuRef
CHM1_1	15	67,952,970 - 68,217,538 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	65,364,709 - 65,628,974 (+)	NCBI		T2T-CHM13v2.0

Map2k5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	63,071,050 - 63,288,964 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	63,071,050 - 63,285,184 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	63,163,768 - 63,381,682 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	63,163,768 - 63,377,902 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	63,011,577 - 63,225,659 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	62,961,776 - 63,175,858 (-)	NCBI		MGSCv36	mm8
Celera	9	60,383,063 - 60,597,534 (-)	NCBI		Celera
Cytogenetic Map	9	B- C	NCBI
cM Map	9	33.96	NCBI

Map2k5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	72,520,616 - 72,748,395 (-)	NCBI		GRCr8
mRatBN7.2	8	63,625,220 - 63,852,090 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	63,625,221 - 63,851,983 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	69,140,369 - 69,367,101 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	67,412,831 - 67,639,556 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	65,282,951 - 65,509,687 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	68,055,976 - 68,282,656 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	68,055,972 - 68,282,590 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	67,784,868 - 68,010,809 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	67,313,472 - 67,542,723 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	67,332,521 - 67,559,107 (-)	NCBI
Celera	8	63,038,974 - 63,262,592 (-)	NCBI		Celera
Cytogenetic Map	8	q24	NCBI

Map2k5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955450	8,203,569 - 8,458,258 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955450	8,207,577 - 8,458,258 (-)	NCBI	ChiLan1.0	ChiLan1.0

MAP2K5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	31,665,032 - 31,920,792 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	31,664,564 - 31,920,751 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	31,599,952 - 31,856,489 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	31,860,861 - 32,117,463 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	31,861,062 - 32,117,422 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	31,790,015 - 32,045,842 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	31,850,721 - 32,107,484 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	32,096,413 - 32,353,048 (+)	NCBI		UU_Cfam_GSD_1.0

Map2k5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	109,643,236 - 109,880,510 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	27,491,342 - 27,728,607 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	27,491,255 - 27,728,572 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAP2K5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	165,458,258 - 165,740,297 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	165,458,263 - 165,733,452 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	183,148,368 - 183,197,101 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAP2K5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	15,694,760 - 15,956,814 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	15,693,811 - 15,956,918 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	125,513,002 - 125,773,972 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Map2k5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624781	5,224,724 - 5,489,488 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624781	5,224,722 - 5,489,517 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003828008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003828009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055098503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055098504	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055098505	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057299879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057299880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057299881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057299882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057299883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063596751	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063596752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063596753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063596754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000050801 ⟹ ENSPPAP00000027958

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	64,761,394 - 65,029,655 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000050805 ⟹ ENSPPAP00000027962

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	64,761,394 - 65,029,655 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000050811 ⟹ ENSPPAP00000027968

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	15	64,762,118 - 65,029,288 (+)	Ensembl

RefSeq Acc Id:

XM_003828008 ⟹ XP_003828056

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,445 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,970,957 - 61,238,196 (+)	NCBI
Mhudiblu_PPA_v0	15	46,493,139 - 46,760,271 (+)	NCBI
PanPan1.1	15	64,761,465 - 65,029,652 (+)	NCBI

Sequence:

show sequence

GGAGTAACAGTGTCGCCGCCGCCTTCCTCCTCCTCCTCTCGCCGCTACCGCCGTCGCCGCCGCC
GCAGCCGCCGCCGGTCCGCGCGGCCTCGGGTGGCCGGAGCTCAGCCTGCGCGCGCCGCGCCGTG
TGTCTCCGGGTGGGGCAGAAGACTCGCCCCTTGAACCTCCCGCGGGGACTCTCCGTGGTGTGGC
GGCCCTGCGGCTCTTTCTTAATAGCCCCGGACTGAGTCCCCTCCAGTCGAGGACCCTCTCCTAG
TCCACTGACGAGCGGTGGACACCTGCCGCTGTATCTCCCCCAAACCGAGTCCTTGCCCTGCTGC
CTCCTCATACCCACACGGCGGCAGAGACCTTCACCATAGCGTTCGCTCAACTCCAGAACCTTCC
GACCTCCGCTAGTTCCTGCGGGCCTCTGCCCGCTTCCCGGTGCACCCTCCCCGGGAGACACCTC
AGACCCCCGACGGCCTGGGCAGGCTCGGTGCCTGCGGGTGCGTTCCTGATCACCCCTCCCCTCT
TCCCTCCCCCTCATCCTCCATTCCCTTGTTTTCACCCTCTGTCCTCTGCCCCTCACTCCCCTTG
TCACCTCTTGGAGCCCCCTCCTAACCAGCGGCCAGTGGGTTTCCCCTACCCCAGGATGTGAGCC
TCTTTAACCTGTAATGCTGTGGCTAGCCCTTGGCCCCTTTCCTGCCATGGAGAACCAGGTGCTG
GTAATTCGCATCAAGATCCCAAATAGTGGCGCGGTGGACTGGACAGTGCACTCCGGGCCGCAGT
TACTCTTCAGGGATGTGCTGGATGTGATAGGCCAGGTTCTGCCTGAAGCAACAACTACAGCATT
TGAATATGAAGATGAAGATGGTGATCGAATTACAGTGAGAAGTGATGAGGAAATGAAGGCAATG
CTGTCATATTATTATTCCACAGTAATGGAACAGCAAGTAAATGGACAGTTAATAGAGCCTCTGC
AGATATTTCCAAGAGCCTGCAAGCCTCCTGGGGAACGGAACATACATGGCCTGAAGGTGAATAC
TCGGGCCGGACCCTCTCAACACAGCAGCCCAGCAGTCTCAGATTCACTTCCAAGCAATAGCTTA
AAGAAGTCTTCTGCTGAACTGAAAAAAATACTAGCCAATGGCCAGATGAATGAACAAGACATAC
GATATCGGGACACTCTTGGTCATGGCAACGGAGGCACAGTCTACAAAGCATATCATGTCCCGAG
TGGGAAAATATTAGCTGTAAAGGTCATACTACTAGATATTACACTGGAACTTCAGAAGCAAATT
ATGTCTGAATTGGAAATTCTTTATAAGTGCGATTCATCATATATCATTGGATTTTATGGAGCAT
TTTTTGTAGAAAACAGGATTTCAATATGTACAGAATTCATGGATGGGGGATCTTTGGATGTATA
TAGGAAAATGCCAGAACATGTCCTTGGAAGAATTGCAGTAGCAGTTGTTAAAGGCCTTACTTAT
TTGTGGAGTTTAAAGATTTTACATAGAGACGTGAAGCCCTCCAATATGCTAGTAAACACAAGAG
GACAGGTTAAGCTGTGTGATTTTGGAGTTAGCACTCAGCTGGTGAATTCTATAGCCAAGACGTA
TGTTGGAACAAATGCTTATATGGCGCCTGAAAGGATTTCAGGGGAGCAGTATGGAATTCATTCT
GATGTCTGGAGCTTAGGAATCTCTTTTATGGAGCTTGCTCTTGGGAGGTTTCCATATCCTCAGA
TTCAGAAAAACCAGGGATCTTTAATGCCTCTCCAGCTTCTGCAGTGCATTGTTGATGAGGATTC
GCCCGTCCTTCCAGTTGGAGAGTTCTCGGAGCCATTTGTACATTTCATCACTCAGTGTATGCGA
AAACAGCCAAAAGAAAGGCCAGCACCTGAAGAATTGATGGGCCACCCGTTCATCGTGCAGTTCA
ATGATGGAAATGCCGCCGTGGTGTCCATGTGGGTGTGCCGGGCACTGGAGGAGAGGCGGAGCCA
GCAGGGGCCCCCGTGAGGCTGCCGCAGGGCACTGAAAGCCCAGGACCAGTAACCAAGGAGAACA
ACCCACCGGTCGCCCTTCTCCGTATGCTGCCTGCGCCAGAAGAGCTTTGCTGGGCCCTGGCTTC
CCTGCCCTCGCCTTCACCTCTGTCAGCAGGTGGCCTTGCCTGGGGAGCCCCATGTGTGGCCCAC
CCCACCAGGCCATCCCCATACCTTCTGGTTTGAAGGCGCTGACACTGGCAGAGAGGTAAAGGGT
GGGGCATTGAGAATGGAGGCTCCCAGGGCCCCTGCCCACTTCTGTTTTCCTAATGTTTTTCTCT
ATAAAGGGTCAGGCCCGTCAGCATCACTGATGGGAATAAAAGTATTAATGCTTTGTGACA

hide sequence

RefSeq Acc Id:

XM_055098503 ⟹ XP_054954478

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,617 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,970,950 - 61,238,196 (+)	NCBI

RefSeq Acc Id:

XM_055098504 ⟹ XP_054954479

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,893 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,971,558 - 61,238,196 (+)	NCBI

RefSeq Acc Id:

XM_055098505 ⟹ XP_054954480

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,471 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,970,957 - 61,238,196 (+)	NCBI

RefSeq Acc Id:

XM_057299879 ⟹ XP_057155862

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,893 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,971,558 - 61,238,196 (+)	NCBI

RefSeq Acc Id:

XM_057299880 ⟹ XP_057155863

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,893 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,971,558 - 61,238,196 (+)	NCBI

RefSeq Acc Id:

XM_057299881 ⟹ XP_057155864

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,893 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,971,558 - 61,238,196 (+)	NCBI

RefSeq Acc Id:

XM_057299882 ⟹ XP_057155865

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,893 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,971,558 - 61,238,196 (+)	NCBI

RefSeq Acc Id:

XM_057299883 ⟹ XP_057155866

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,798,101 - 57,064,491 (+)	NCBI
NHGRI_mPanPan1	15	60,971,695 - 61,238,196 (+)	NCBI

RefSeq Acc Id:

XM_063596751 ⟹ XP_063452821

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,471 - 57,064,491 (+)	NCBI

RefSeq Acc Id:

XM_063596752 ⟹ XP_063452822

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,893 - 57,064,491 (+)	NCBI

RefSeq Acc Id:

XM_063596753 ⟹ XP_063452823

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,893 - 57,064,491 (+)	NCBI

RefSeq Acc Id:

XM_063596754 ⟹ XP_063452824

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	16	56,797,617 - 57,064,491 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003828056	(Get FASTA)	NCBI Sequence Viewer
	XP_054954478	(Get FASTA)	NCBI Sequence Viewer
	XP_054954479	(Get FASTA)	NCBI Sequence Viewer
	XP_054954480	(Get FASTA)	NCBI Sequence Viewer
	XP_057155862	(Get FASTA)	NCBI Sequence Viewer
	XP_057155863	(Get FASTA)	NCBI Sequence Viewer
	XP_057155864	(Get FASTA)	NCBI Sequence Viewer
	XP_057155865	(Get FASTA)	NCBI Sequence Viewer
	XP_057155866	(Get FASTA)	NCBI Sequence Viewer
	XP_063452821	(Get FASTA)	NCBI Sequence Viewer
	XP_063452822	(Get FASTA)	NCBI Sequence Viewer
	XP_063452823	(Get FASTA)	NCBI Sequence Viewer
	XP_063452824	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000027958
	ENSPPAP00000027958.1
	ENSPPAP00000027962.1
	ENSPPAP00000027968.1

RefSeq Acc Id:	XP_003828056 ⟸ XM_003828008
- Peptide Label:	isoform X11
- UniProtKB:	A0A2R9BFH4 (UniProtKB/TrEMBL), A0A2R9BFI4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYED EDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGP SQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKIL AVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMP EHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTN AYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLP VGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP hide sequence

Ensembl Acc Id:

ENSPPAP00000027962 ⟸ ENSPPAT00000050805

Ensembl Acc Id:

ENSPPAP00000027958 ⟸ ENSPPAT00000050801

Ensembl Acc Id:

ENSPPAP00000027968 ⟸ ENSPPAT00000050811

RefSeq Acc Id:	XP_054954480 ⟸ XM_055098505
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_054954478 ⟸ XM_055098503
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_054954479 ⟸ XM_055098504
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_057155862 ⟸ XM_057299879
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_057155863 ⟸ XM_057299880
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_057155864 ⟸ XM_057299881
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_057155865 ⟸ XM_057299882
- Peptide Label:	isoform X10

RefSeq Acc Id:	XP_057155866 ⟸ XM_057299883
- Peptide Label:	isoform X12

RefSeq Acc Id:	XP_063452821 ⟸ XM_063596751
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063452824 ⟸ XM_063596754
- Peptide Label:	isoform X13
- UniProtKB:	A0A2R9BI59 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063452822 ⟸ XM_063596752
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063452823 ⟸ XM_063596753
- Peptide Label:	isoform X7

Protein Domains

PB1 Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000036945	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000050801.1	UniProtKB/TrEMBL
	ENSPPAT00000050805.1	UniProtKB/TrEMBL
	ENSPPAT00000050811.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	PB1-like	UniProtKB/TrEMBL
	PB1_dom	UniProtKB/TrEMBL
	PB1_MAP2K5	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
KEGG Report	pps:100994910	UniProtKB/TrEMBL
NCBI Gene	MAP2K5	ENTREZGENE
PANTHER	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5	UniProtKB/TrEMBL
	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED	UniProtKB/TrEMBL
Pfam	PB1	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PROSITE	PB1	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	PB1	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	CAD & PB1 domains	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A2R9BFH4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BFI4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BI59	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations