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Gene: GOLT1A (golgi transport 1A) Pan paniscus

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Symbol:

GOLT1A

Name:

golgi transport 1A

RGD ID:

11730729

Description:

ENCODES a protein that exhibits kisspeptin receptor binding (inferred); INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport (inferred); G protein-coupled receptor signaling pathway (inferred); positive regulation of cytosolic calcium ion concentration (inferred); ASSOCIATED WITH autistic disorder (ortholog); familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); endomembrane system (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

KiSS-1 metastasis suppressor; KiSS-1 metastasis-suppressor; KISS1; LOC100983679; metastasis-suppressor KiSS-1; vesicle transport protein GOT1A

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GOLT1A (golgi transport 1A)	NCBI	Ortholog
Mus musculus (house mouse):	Golt1a (golgi transport 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Golt1a (golgi transport 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Golt1a (golgi transport 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GOLT1A (golgi transport 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Golt1a (golgi transport 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KISS1 (KiSS-1 metastasis suppressor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GOLT1A (golgi transport 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Golt1a (golgi transport 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	45,162,945 - 45,178,771 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	45,128,079 - 45,143,983 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	179,800,580 - 179,816,530 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	184,088,931 - 184,104,815 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	184,080,570 - 184,104,815 (-)	Ensembl	panpan1.1		panPan2
PanPan1.1 Ensembl	1	184,088,931 - 184,104,815 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

familial adult myoclonic epilepsy 5 (ISO)

gastrointestinal stromal tumor (ISO)

Hypokalemic Periodic Paralysis, Type 1 (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endoplasmic reticulum to Golgi vesicle-mediated transport (IEA)

G protein-coupled receptor signaling pathway (IEA)

positive regulation of cytosolic calcium ion concentration (IEA)

retrograde transport, endosome to Golgi (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

endomembrane system (IEA)

endoplasmic reticulum (IEA)

Golgi apparatus (IEA)

Golgi cis cisterna (IEA)

Golgi membrane (IEA)

intracellular membrane-bounded organelle (IEA)

membrane (IEA)

nuclear envelope (IEA)

trans-Golgi network (IEA)

Molecular Function

kisspeptin receptor binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

GOLT1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	45,162,945 - 45,178,771 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	45,128,079 - 45,143,983 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	179,800,580 - 179,816,530 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	184,088,931 - 184,104,815 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	184,080,570 - 184,104,815 (-)	Ensembl	panpan1.1		panPan2
PanPan1.1 Ensembl	1	184,088,931 - 184,104,815 (-)	Ensembl	panpan1.1		panPan2

GOLT1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	204,198,163 - 204,213,988 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	204,198,163 - 204,213,988 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	204,167,291 - 204,183,116 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	202,433,911 - 202,449,843 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	200,898,944 - 200,914,877	NCBI
Celera	1	177,302,746 - 177,318,675 (-)	NCBI		Celera
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	175,332,277 - 175,348,173 (-)	NCBI		HuRef
CHM1_1	1	205,591,205 - 205,607,128 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	203,462,758 - 203,478,572 (-)	NCBI		T2T-CHM13v2.0

Golt1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	133,237,561 - 133,250,764 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	133,237,565 - 133,257,639 (+)	Ensembl		GRCm39 Ensembl
GRCm39 Ensembl	1	133,237,538 - 133,250,764 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	133,309,823 - 133,323,026 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	133,309,827 - 133,329,901 (+)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	1	133,309,800 - 133,323,026 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	135,206,400 - 135,219,603 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	135,137,373 - 135,157,173 (+)	NCBI		MGSCv36	mm8
Celera	1	135,922,392 - 135,935,498 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	57.91	NCBI

Golt1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	47,312,412 - 47,325,176 (+)	NCBI		GRCr8
mRatBN7.2	13	44,760,356 - 44,773,123 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	44,760,380 - 44,773,122 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	47,370,502 - 47,383,165 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	48,658,606 - 48,671,269 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	45,916,400 - 45,929,067 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	50,532,116 - 50,550,029 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	50,537,133 - 50,550,015 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	55,589,979 - 55,602,878 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	46,224,376 - 46,237,118 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	13	45,093,262 - 45,106,001 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

Golt1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	40,050,069 - 40,053,369 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	40,049,060 - 40,061,902 (-)	NCBI	ChiLan1.0	ChiLan1.0

GOLT1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	774,454 - 790,899 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	774,454 - 789,655 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	869,945 - 885,511 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	769,790 - 785,486 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	769,790 - 785,385 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	766,329 - 781,922 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	1,157,720 - 1,173,350 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	1,357,933 - 1,373,532 (-)	NCBI		UU_Cfam_GSD_1.0

Golt1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	71,334,927 - 71,345,815 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936567	577,205 - 580,142 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936567	569,629 - 580,142 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KISS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	64,834,820 - 64,853,610 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	64,842,277 - 64,853,653 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	71,175,507 - 71,186,884 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GOLT1A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	25,134,810 - 25,151,403 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	25,135,616 - 25,151,395 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	25,896,171 - 25,912,034 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Golt1a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	6,795,884 - 6,798,898 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624807	6,787,933 - 6,799,206 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003822969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008976585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000029653 ⟹ ENSPPAP00000007363

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	184,088,931 - 184,104,815 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000048838 ⟹ ENSPPAP00000026006

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	184,080,570 - 184,104,815 (-)	Ensembl

RefSeq Acc Id:

XM_003822969 ⟹ XP_003823017

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	45,162,945 - 45,178,771 (+)	NCBI
NHGRI_mPanPan1	1	45,128,087 - 45,143,983 (+)	NCBI
Mhudiblu_PPA_v0	1	179,800,580 - 179,816,523 (-)	NCBI
PanPan1.1	1	184,088,931 - 184,104,815 (-)	NCBI

Sequence:

show sequence

TGCCCTACCGGAAAACGGGAGGAGGGAGCCGGCGAGTAGAAGCACCTGCGTGGTGTGCGGGGGT
GGAGCGGGGGCTGGAGGGAGAGTTAATGATTTGCCACAGGCTCATTTCGCAACTTAACCAAGGG
TCAGCTTCCCGTGACCATGTGCCAGCTGCGTCCTCTGGGCCACGCTCCACTTGCCCGCTTCCAC
CCGGAAGGCCCCCCAGGCTGAGTGCGGCATGATCTCCATCACCGAATGGCAGAAGATTGGTGTG
GGGATCACCGGTTTCGGCATCTTCTTCATCCTCTTTGGAACAGTCCTGTACTTTGATTCCGTGC
TCCTGGCCTTTGGAAACCTGCTGTTCCTGACGGGCCTGTCCCTCATCATTGGCCTGAGGAAGAC
CTTTTGGTTCTTCTTCCAACGGCACAAACTCAAGGGAACCAGCTTCTTCCTGGGGGGTGTGGTT
ATCGTGCTCCTACGCTGGCCCCTCCTCGGCATGTTCCTGGAAACCTACGGATTCTTCAGCCTCT
TTAAGGGCTTTTTCCCGGTCGCCTTCGGCTTCCTGGGCAATGTCTGCAACATCCCCTTCCTGGG
TGCGCTGTTCCGGAGACTTCAAGGCACTAGCTCGATGGTCTGAACAACAGAGATGAGCTCCTTG
AACTTGGATCATTGGTTGAGGGGGCTAGAGGGAGAATGGGAACCACCCCCTCAGTCCCCTGCAC
TGACTCACTCCCTGACATATCCGGACCTCCCCAAGTCCAGAAGGAAGGAATGGAGCTGAGCAAC
TGACGTCAAATCCCCAAGTCGACTCAAGAGGCTGCCAGGAAGCAGAGATGCAGACCCCAAGGAG
ACTGGGCTGGGGCTGGCATCACACCCTCACTCTATATTTATGGGAGGAAAAGTGAAGATTAAAT
TCCCAAGTTGTGCGTGTGTCTAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003823017	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000007363
	ENSPPAP00000007363.1
	ENSPPAP00000026006.1

RefSeq Acc Id:	XP_003823017 ⟸ XM_003822969
- UniProtKB:	A0A2R8ZS45 (UniProtKB/TrEMBL)
- Sequence:	show sequence MISITEWQKIGVGITGFGIFFILFGTVLYFDSVLLAFGNLLFLTGLSLIIGLRKTFWFFFQRHK LKGTSFFLGGVVIVLLRWPLLGMFLETYGFFSLFKGFFPVAFGFLGNVCNIPFLGALFRRLQGT SSMV hide sequence

Ensembl Acc Id:

ENSPPAP00000007363 ⟸ ENSPPAT00000029653

Ensembl Acc Id:

ENSPPAP00000026006 ⟸ ENSPPAT00000048838

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000026595	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSPPAG00000036121	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000029653.1	UniProtKB/TrEMBL
	ENSPPAT00000048838.1	UniProtKB/TrEMBL
InterPro	Got1	UniProtKB/TrEMBL
	Metastasis-suppressor_KiSS-1	UniProtKB/TrEMBL
	Vesicle_transpt_Got1/SFT2	UniProtKB/TrEMBL
KEGG Report	pps:100983679	UniProtKB/TrEMBL
NCBI Gene	LOC100983679	ENTREZGENE
PANTHER	METASTASIS-SUPPRESSOR KISS-1	UniProtKB/TrEMBL
	PTHR16955	UniProtKB/TrEMBL
	PTHR21493	UniProtKB/TrEMBL
	VESICLE TRANSPORT PROTEIN GOT1A	UniProtKB/TrEMBL
Pfam	Got1	UniProtKB/TrEMBL
	Kisspeptin	UniProtKB/TrEMBL
UniProt	A0A2R8ZS45	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9BCJ2_PANPA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-06-21	GOLT1A	golgi transport 1A	LOC100983679	vesicle transport protein GOT1A	Symbol and/or name change	5135510	APPROVED
2023-05-02	LOC100983679	vesicle transport protein GOT1A	GOLT1A	golgi transport 1A	Symbol and/or name change	5135510	APPROVED
2023-04-20	GOLT1A	golgi transport 1A	KISS1	KiSS-1 metastasis suppressor	Data merged from RGD:13576015	737654	PROVISIONAL
2018-05-08	GOLT1A	golgi transport 1A	LOC100983679	vesicle transport protein GOT1A	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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