USP38 (ubiquitin specific peptidase 38) - Rat Genome Database

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Gene: USP38 (ubiquitin specific peptidase 38) Pan paniscus
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Symbol: USP38
Name: ubiquitin specific peptidase 38
RGD ID: 11728065
Description: ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); protein sequestering activity (inferred); INVOLVED IN negative regulation of innate immune response (inferred); negative regulation of proteasomal ubiquitin-dependent protein catabolic process (inferred); protein deubiquitination (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 38
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23141,060,691 - 141,106,019 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14141,448,446 - 141,493,761 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04135,545,818 - 135,582,520 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14146,844,850 - 146,881,486 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4146,844,850 - 146,881,486 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
USP38Bonobonegative regulation of innate immune response involved_inIEAUniProtKB:Q8NB14|ensembl:ENSP00000303434150520179 EnsemblGO_REF:0000107
USP38Bonobonegative regulation of proteasomal ubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:Q8NB14|ensembl:ENSP00000303434150520179 EnsemblGO_REF:0000107
USP38Bonoboprotein deubiquitination involved_inIEAInterPro:IPR001394150520179 InterProGO_REF:0000002
USP38Bonoboprotein deubiquitination involved_inIEAPANTHER:PTN002768537150520179 TreeGrafterGO_REF:0000118
USP38Bonoboprotein K33-linked deubiquitination involved_inIEAUniProtKB:Q8NB14|ensembl:ENSP00000303434150520179 EnsemblGO_REF:0000107
USP38Bonoboubiquitin-dependent protein catabolic process involved_inIEAInterPro:IPR033840150520179 InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
USP38Bonobocytoplasm is_active_inIEAUniProtKB:Q8NB14|ensembl:ENSP00000303434150520179 EnsemblGO_REF:0000107
USP38Bonobocytosol located_inIEAPANTHER:PTN002768537150520179 TreeGrafterGO_REF:0000118
USP38Bonobonucleus located_inIEAPANTHER:PTN002768537150520179 TreeGrafterGO_REF:0000118

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
USP38Bonobocysteine-type deubiquitinase activity enablesIEAPANTHER:PTN002768537150520179 TreeGrafterGO_REF:0000118
USP38Bonobocysteine-type deubiquitinase activity enablesIEAUniProtKB:Q8NB14|ensembl:ENSP00000303434150520179 EnsemblGO_REF:0000107
USP38Bonobocysteine-type deubiquitinase activity enablesIEAInterPro:IPR001394|InterPro:IPR018200150520179 InterProGO_REF:0000002
USP38Bonoboprotein binding enablesISOUniProtKB:P17252|UniProtKB:P61981|UniProtKB:Q15047-2|UniProtKB:Q8TAP4-4|UniProtKB:Q929939068941 PMID:32814053IntActPMID:32814053
USP38Bonoboprotein sequestering activity enablesIEAUniProtKB:Q8NB14|ensembl:ENSP00000303434150520179 EnsemblGO_REF:0000107

PMID:22301074   PMID:30032202  



USP38
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23141,060,691 - 141,106,019 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14141,448,446 - 141,493,761 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04135,545,818 - 135,582,520 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14146,844,850 - 146,881,486 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4146,844,850 - 146,881,486 (+)Ensemblpanpan1.1panPan2
USP38
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384143,184,917 - 143,223,874 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4143,184,917 - 143,225,212 (+)EnsemblGRCh38hg38GRCh38
GRCh374144,106,070 - 144,145,027 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364144,325,548 - 144,362,090 (+)NCBINCBI36Build 36hg18NCBI36
Build 344144,463,702 - 144,500,244NCBI
Celera4141,435,984 - 141,473,049 (+)NCBICelera
Cytogenetic Map4q31.21NCBI
HuRef4139,835,778 - 139,872,846 (+)NCBIHuRef
CHM1_14144,083,284 - 144,120,348 (+)NCBICHM1_1
T2T-CHM13v2.04146,502,094 - 146,541,045 (+)NCBIT2T-CHM13v2.0
Usp38
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39881,707,353 - 81,741,631 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl881,707,362 - 81,741,557 (-)EnsemblGRCm39 Ensembl
GRCm38880,980,724 - 81,015,013 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl880,980,733 - 81,014,928 (-)EnsemblGRCm38mm10GRCm38
MGSCv37883,504,632 - 83,538,805 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36883,876,479 - 83,910,652 (-)NCBIMGSCv36mm8
Celera885,259,181 - 85,286,557 (-)NCBICelera
Celera875,127,726 - 75,134,583 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map838.68NCBI
Usp38
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81943,910,459 - 43,941,875 (+)NCBIGRCr8
mRatBN7.21927,006,046 - 27,037,449 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1927,006,046 - 27,037,437 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1933,859,775 - 33,891,219 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01934,513,838 - 34,545,280 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01936,738,942 - 36,770,306 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01930,668,258 - 30,699,852 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1930,668,602 - 30,699,859 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01941,576,070 - 41,607,659 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41928,847,283 - 28,879,605 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11928,852,729 - 28,883,368 (+)NCBI
Celera1926,525,530 - 26,557,224 (+)NCBICelera
Cytogenetic Map19q11NCBI
Usp38
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955471315,779 - 350,982 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955471316,319 - 350,982 (-)NCBIChiLan1.0ChiLan1.0
USP38
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.119201,810 - 238,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl19210,388 - 238,384 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha19450,450 - 488,291 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.019225,088 - 262,681 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl19233,599 - 262,766 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.119204,694 - 242,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.019565,325 - 603,796 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.019919,303 - 957,368 (-)NCBIUU_Cfam_GSD_1.0
Usp38
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530147,708,507 - 47,740,441 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365355,146,327 - 5,178,205 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365355,146,327 - 5,178,184 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP38
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl884,567,618 - 84,601,224 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1884,567,476 - 84,601,044 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2889,716,675 - 89,724,274 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP38
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1790,049,643 - 90,087,152 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl790,049,638 - 90,089,110 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603769,649,470 - 69,688,113 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp38
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248532,485,332 - 2,518,070 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248532,485,347 - 2,519,165 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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RefSeq Transcripts XM_003820700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063603915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000060277   ⟹   ENSPPAP00000037377
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4146,844,850 - 146,881,486 (+)Ensembl
RefSeq Acc Id: XM_003820700   ⟹   XP_003820748
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v23141,060,691 - 141,106,019 (+)NCBI
NHGRI_mPanPan14141,448,446 - 141,493,761 (+)NCBI
Mhudiblu_PPA_v04135,545,818 - 135,582,520 (+)NCBI
PanPan1.14146,844,850 - 146,881,486 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063603915   ⟹   XP_063459985
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v23141,060,898 - 141,106,019 (+)NCBI
Protein RefSeqs XP_003820748 (Get FASTA)   NCBI Sequence Viewer  
  XP_063459985 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037377.1
RefSeq Acc Id: XP_003820748   ⟸   XM_003820700
- UniProtKB: A0A2R9CGP9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000037377   ⟸   ENSPPAT00000060277
RefSeq Acc Id: XP_063459985   ⟸   XM_063603915
- UniProtKB: A0A2R9CGP9 (UniProtKB/TrEMBL)
USP



1 to 21 of 21 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000041444 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060277.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  USP38 UniProtKB/TrEMBL
  Usp38-like_N UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
KEGG Report pps:100990061 UniProtKB/TrEMBL
NCBI Gene USP38 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 38 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
  Usp38-like_N UniProtKB/TrEMBL
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0A2R9CGP9 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows