HENMT1 (HEN methyltransferase 1) - Rat Genome Database

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Gene: HENMT1 (HEN methyltransferase 1) Pan paniscus
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Symbol: HENMT1
Name: HEN methyltransferase 1
RGD ID: 11719821
Description: ENCODES a protein that exhibits methyltransferase activity (inferred); O-methyltransferase activity (inferred); RNA methyltransferase activity (inferred); INVOLVED IN methylation (inferred); piRNA processing (inferred); regulatory ncRNA-mediated gene silencing (inferred); ASSOCIATED WITH autistic disorder (ortholog); azoospermia (ortholog); hereditary spastic paraplegia 63 (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: HEN1 methyltransferase homolog 1; small RNA 2'-O-methyltransferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21118,641,837 - 118,657,252 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11117,801,704 - 117,817,082 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01111,023,949 - 111,037,138 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11110,191,227 - 110,204,275 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1110,191,227 - 110,204,270 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
HENMT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21118,641,837 - 118,657,252 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11117,801,704 - 117,817,082 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01111,023,949 - 111,037,138 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11110,191,227 - 110,204,275 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1110,191,227 - 110,204,270 (-)Ensemblpanpan1.1panPan2
HENMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381108,648,295 - 108,661,474 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1108,648,290 - 108,661,526 (-)EnsemblGRCh38hg38GRCh38
GRCh371109,190,917 - 109,204,096 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361108,992,433 - 109,005,671 (-)NCBINCBI36Build 36hg18NCBI36
Celera1107,460,828 - 107,474,037 (-)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1107,083,630 - 107,096,727 (-)NCBIHuRef
CHM1_11109,305,731 - 109,318,961 (-)NCBICHM1_1
T2T-CHM13v2.01108,681,289 - 108,694,467 (-)NCBIT2T-CHM13v2.0
Henmt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393108,846,770 - 108,887,201 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3108,847,375 - 108,868,090 (+)EnsemblGRCm39 Ensembl
GRCm383108,939,454 - 108,979,885 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,940,059 - 108,960,774 (+)EnsemblGRCm38mm10GRCm38
MGSCv373108,743,002 - 108,763,694 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363109,068,140 - 109,088,732 (+)NCBIMGSCv36mm8
Celera3111,275,307 - 111,295,934 (+)NCBICelera
Cytogenetic Map3F3NCBI
cM Map347.99NCBI
Henmt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82199,258,107 - 199,291,739 (+)NCBIGRCr8
mRatBN7.22196,585,732 - 196,603,700 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2196,586,797 - 196,599,738 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2204,230,540 - 204,242,798 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02202,118,362 - 202,130,609 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02196,935,420 - 196,947,668 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02211,740,571 - 211,753,718 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02231,214,546 - 231,225,175 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,544,606 - 204,558,076 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12204,506,770 - 204,520,830 (+)NCBI
Celera2189,235,772 - 189,247,793 (+)NCBICelera
Cytogenetic Map2q41NCBI
Henmt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543512,138,177 - 12,154,630 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543512,137,537 - 12,154,630 (-)NCBIChiLan1.0ChiLan1.0
HENMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha645,928,483 - 45,943,590 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0643,396,229 - 43,435,695 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl643,428,453 - 43,435,709 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1643,152,578 - 43,167,498 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0643,084,944 - 43,088,221 (+)NCBIUNSW_CanFamBas_1.0
UNSW_CanFamBas_1.0643,125,908 - 43,140,909 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0643,552,275 - 43,567,220 (+)NCBIUU_Cfam_GSD_1.0
Henmt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505819,857,460 - 19,870,919 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936704242,262 - 256,739 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HENMT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4111,364,966 - 111,382,572 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14111,364,456 - 111,382,582 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24121,863,155 - 121,881,143 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HENMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12024,920,224 - 24,936,429 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2024,921,611 - 24,936,419 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603833,410,548 - 33,426,967 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Henmt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247724,456,917 - 4,470,558 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247724,452,320 - 4,470,097 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000030791   ⟹   ENSPPAP00000008156
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1110,191,227 - 110,204,270 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000030796   ⟹   ENSPPAP00000008161
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1110,191,503 - 110,202,937 (-)Ensembl
RefSeq Acc Id: XM_003808327   ⟹   XP_003808375
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21118,641,862 - 118,657,252 (+)NCBI
NHGRI_mPanPan11117,801,738 - 117,817,082 (+)NCBI
Mhudiblu_PPA_v01111,023,949 - 111,036,523 (-)NCBI
PanPan1.11110,191,227 - 110,203,912 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003808328   ⟹   XP_003808376
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21118,641,858 - 118,657,252 (+)NCBI
NHGRI_mPanPan11117,801,737 - 117,817,082 (+)NCBI
Mhudiblu_PPA_v01111,023,949 - 111,037,138 (-)NCBI
PanPan1.11110,191,227 - 110,204,275 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024930816   ⟹   XP_024786584
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21118,641,858 - 118,657,252 (+)NCBI
NHGRI_mPanPan11117,801,736 - 117,817,082 (+)NCBI
Mhudiblu_PPA_v01111,023,949 - 111,036,523 (-)NCBI
PanPan1.11110,191,227 - 110,203,912 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055115271   ⟹   XP_054971246
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21118,644,632 - 118,657,252 (+)NCBI
NHGRI_mPanPan11117,804,497 - 117,817,082 (+)NCBI
RefSeq Acc Id: XM_055115276   ⟹   XP_054971251
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21118,641,837 - 118,657,252 (+)NCBI
NHGRI_mPanPan11117,801,704 - 117,817,082 (+)NCBI
RefSeq Acc Id: XM_055115278   ⟹   XP_054971253
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21118,644,632 - 118,657,252 (+)NCBI
NHGRI_mPanPan11117,804,497 - 117,817,082 (+)NCBI
RefSeq Acc Id: XP_003808376   ⟸   XM_003808328
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZWD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003808375   ⟸   XM_003808327
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZWD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024786584   ⟸   XM_024930816
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZWD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000008161   ⟸   ENSPPAT00000030796
RefSeq Acc Id: ENSPPAP00000008156   ⟸   ENSPPAT00000030791
RefSeq Acc Id: XP_054971251   ⟸   XM_055115276
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054971253   ⟸   XM_055115278
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054971246   ⟸   XM_055115271
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027321 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030791.1 UniProtKB/TrEMBL
  ENSPPAT00000030796.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro Hen1 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
KEGG Report pps:100993522 UniProtKB/TrEMBL
NCBI Gene HENMT1 ENTREZGENE
PANTHER PTHR21404 UniProtKB/TrEMBL
  SMALL RNA 2'-O-METHYLTRANSFERASE UniProtKB/TrEMBL
Pfam Methyltransf_23 UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A2R8ZWD2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZWG6_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-23 HENMT1  HEN methyltransferase 1    HEN1 methyltransferase homolog 1  Symbol and/or name change 5135510 APPROVED