XPO6 (exportin 6) - Rat Genome Database

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Gene: XPO6 (exportin 6) Pan paniscus
Analyze
Symbol: XPO6
Name: exportin 6
RGD ID: 11710635
Description: ENCODES a protein that exhibits nuclear export signal receptor activity (inferred); small GTPase binding (inferred); INVOLVED IN intracellular protein transport (inferred); macromolecule localization (inferred); nucleocytoplasmic transport (inferred); ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); substance-related disorder (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleolus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: exportin-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21829,495,054 - 29,609,022 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11634,031,603 - 34,145,576 (-)NCBINHGRI_mPanPan1
PanPan1.11628,465,138 - 28,579,109 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1628,462,546 - 28,579,109 (-)Ensemblpanpan1.1panPan2


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
XPO6Bonoboneuronal ceroid lipofuscinosis  ISOXPO6 (Homo sapiens)8554872ClinVar Annotator: match by term: Neuronal ceroid lipofuscinosisClinVarPMID:28492532 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
XPO6Bonobosubstance-related disorder  ISOXPO6 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:20098672


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
XPO6Bonobointracellular protein transport involved_inIEAInterPro:IPR001494150520179 InterProGO_REF:0000002
XPO6Bonobomacromolecule localization involved_inIEAARBA:ARBA00029092150520179 UniProtGO_REF:0000117
XPO6Bonobonucleocytoplasmic transport involved_inIEAARBA:ARBA00027758150520179 UniProtGO_REF:0000117
XPO6Bonoboprotein export from nucleus involved_inIEAUniProtKB:Q96QU8 and ensembl:ENSP00000302790150520179 EnsemblGO_REF:0000107
XPO6Bonoboprotein export from nucleus involved_inIEAPANTHER:PTN002725700150520179 TreeGrafterGO_REF:0000118
XPO6Bonoboprotein export from nucleus involved_inIEAInterPro:IPR040016150520179 InterProGO_REF:0000002
XPO6Bonoboprotein transport involved_inIEAUniProtKB-KW:KW-0653150520179 UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
XPO6Bonobocytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
XPO6Bonobocytoplasm located_inIEAUniProtKB-SubCell:SL-0086150520179 UniProtGO_REF:0000044
XPO6Bonobocytosol located_inIEAUniProtKB:Q96QU8 and ensembl:ENSP00000302790150520179 EnsemblGO_REF:0000107
XPO6Bonobonucleolus located_inIEAUniProtKB:Q96QU8 and ensembl:ENSP00000302790150520179 EnsemblGO_REF:0000107
XPO6Bonobonucleoplasm located_inIEAUniProtKB:Q96QU8 and ensembl:ENSP00000302790150520179 EnsemblGO_REF:0000107
XPO6Bonobonucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
XPO6Bonoboplasma membrane located_inIEAUniProtKB:Q96QU8 and ensembl:ENSP00000302790150520179 EnsemblGO_REF:0000107
XPO6Bonoboprotein-containing complex part_ofIEAUniProtKB:Q96QU8 and ensembl:ENSP00000302790150520179 EnsemblGO_REF:0000107

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
XPO6Bonobonuclear export signal receptor activity enablesIEAUniProtKB:Q96QU8 and ensembl:ENSP00000302790150520179 EnsemblGO_REF:0000107
XPO6Bonobonuclear export signal receptor activity enablesIEAInterPro:IPR040016150520179 InterProGO_REF:0000002
XPO6Bonoboprotein binding enablesISOUniProtKB:P371989068941 PMID:16189514 more ...IntActPMID:16189514 more ...
XPO6Bonoboprotein binding enablesISOUniProtKB:P607099068941 PMID:14592989UniProtPMID:14592989
XPO6Bonobosmall GTPase binding enablesIEAInterPro:IPR001494150520179 InterProGO_REF:0000002

PMID:22301074   PMID:30032202  



XPO6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21829,495,054 - 29,609,022 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11634,031,603 - 34,145,576 (-)NCBINHGRI_mPanPan1
PanPan1.11628,465,138 - 28,579,109 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1628,462,546 - 28,579,109 (-)Ensemblpanpan1.1panPan2
XPO6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,097,976 - 28,211,965 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1628,097,976 - 28,211,965 (-)EnsemblGRCh38hg38GRCh38
GRCh371628,109,297 - 28,223,286 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,016,817 - 28,130,691 (-)NCBINCBI36Build 36hg18NCBI36
Celera1626,887,565 - 27,001,783 (-)NCBICelera
Cytogenetic Map16p12.1NCBI
HuRef1626,200,209 - 26,314,563 (-)NCBIHuRef
CHM1_11629,122,254 - 29,236,228 (-)NCBICHM1_1
T2T-CHM13v2.01628,378,417 - 28,492,441 (-)NCBIT2T-CHM13v2.0
Xpo6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397125,700,890 - 125,799,715 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7125,700,887 - 125,799,673 (-)EnsemblGRCm39 Ensembl
GRCm387126,101,718 - 126,200,539 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,101,715 - 126,200,501 (-)EnsemblGRCm38mm10GRCm38
MGSCv377133,245,232 - 133,343,922 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367125,892,866 - 125,991,556 (-)NCBIMGSCv36mm8
Celera7125,956,010 - 126,054,617 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.01NCBI
Xpo6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,102,719 - 190,192,138 (-)NCBIGRCr8
mRatBN7.21180,672,114 - 180,761,543 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,672,119 - 180,761,543 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,003,284 - 189,092,561 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,189,323 - 196,278,608 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01188,872,436 - 188,961,827 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01197,500,509 - 197,590,382 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1197,500,514 - 197,590,277 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01204,484,091 - 204,574,002 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,179,733 - 185,269,588NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1178,332,154 - 178,421,776 (-)NCBICelera
Cytogenetic Map1q36NCBI
Xpo6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554936,172,860 - 6,299,451 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554936,172,860 - 6,265,269 (-)NCBIChiLan1.0ChiLan1.0
XPO6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,569,500 - 18,671,100 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,569,213 - 18,671,095 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha620,145,666 - 20,247,248 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,703,290 - 18,806,739 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,703,256 - 18,806,739 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,502,928 - 18,604,931 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,417,857 - 18,519,851 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,734,168 - 18,836,172 (+)NCBIUU_Cfam_GSD_1.0
Xpo6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344123,429,188 - 123,533,879 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650111,527,032 - 11,631,745 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650111,527,038 - 11,631,739 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XPO6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,772,096 - 18,880,067 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,772,058 - 18,880,650 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2319,004,241 - 19,112,483 (+)NCBISscrofa10.2Sscrofa10.2susScr3
XPO6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1525,794,919 - 25,911,767 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660683,776,791 - 3,893,904 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xpo6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478212,544,298 - 12,672,772 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSPPAT00000043900   ⟹   ENSPPAP00000021100
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1628,462,546 - 28,579,109 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000043911   ⟹   ENSPPAP00000021110
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1628,462,546 - 28,534,287 (-)Ensembl
RefSeq Acc Id: XM_003807768   ⟹   XP_003807816
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21829,495,054 - 29,609,022 (-)NCBI
NHGRI_mPanPan11634,031,603 - 34,145,576 (-)NCBI
PanPan1.11628,465,138 - 28,579,109 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008959908   ⟹   XP_008958156
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21829,495,054 - 29,608,982 (-)NCBI
NHGRI_mPanPan11634,031,603 - 34,145,334 (-)NCBI
PanPan1.11628,465,138 - 28,579,109 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063597958   ⟹   XP_063454028
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21829,495,724 - 29,608,982 (-)NCBI
RefSeq Acc Id: XM_063597959   ⟹   XP_063454029
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21829,495,724 - 29,608,982 (-)NCBI
RefSeq Acc Id: XM_063597960   ⟹   XP_063454030
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21829,495,724 - 29,608,616 (-)NCBI
Protein RefSeqs XP_003807816 (Get FASTA)   NCBI Sequence Viewer  
  XP_008958156 (Get FASTA)   NCBI Sequence Viewer  
  XP_063454028 (Get FASTA)   NCBI Sequence Viewer  
  XP_063454029 (Get FASTA)   NCBI Sequence Viewer  
  XP_063454030 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000021100.1
  ENSPPAP00000021110.1
RefSeq Acc Id: XP_008958156   ⟸   XM_008959908
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AZ37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003807816   ⟸   XM_003807768
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AZ27 (UniProtKB/TrEMBL),   A0A2R9AZ37 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000021100   ⟸   ENSPPAT00000043900
Ensembl Acc Id: ENSPPAP00000021110   ⟸   ENSPPAT00000043911
RefSeq Acc Id: XP_063454029   ⟸   XM_063597959
- Peptide Label: isoform X2
Importin N-terminal



1 to 20 of 20 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000033668 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043900.1 UniProtKB/TrEMBL
  ENSPPAT00000043911.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Exportin-1/Importin-b-like UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  XPO6 UniProtKB/TrEMBL
KEGG Report pps:100972760 UniProtKB/TrEMBL
NCBI Gene XPO6 ENTREZGENE
PANTHER EXPORTIN-6 UniProtKB/TrEMBL
  PTHR21452 UniProtKB/TrEMBL
Pfam IBN_N UniProtKB/TrEMBL
  Xpo1 UniProtKB/TrEMBL
PROSITE IMPORTIN_B_NT UniProtKB/TrEMBL
SMART IBN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A2R9AZ27 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AZ37 ENTREZGENE, UniProtKB/TrEMBL
1 to 20 of 20 rows