NPAS3 (neuronal PAS domain protein 3) - Rat Genome Database

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Gene: NPAS3 (neuronal PAS domain protein 3) Pan paniscus
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Symbol: NPAS3
Name: neuronal PAS domain protein 3
RGD ID: 11700100
Description: ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN locomotory behavior (ortholog); maternal behavior (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); schizophrenia (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neuronal PAS domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01413,701,786 - 14,568,738 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11431,990,835 - 32,759,347 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1431,893,101 - 32,758,096 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NPAS3BonoboBrain-Lung-Thyroid Syndrome  ISONPAS3 (Homo sapiens)8554872ClinVar Annotator: match by term: Brain-lung-thyroid syndromeClinVarPMID:25741868
NPAS3Bonoboschizophrenia  ISONPAS3 (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311


Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NPAS3Bonobonucleoplasm located_inIEAUniProtKB:Q8IXF0 more ...150520179 EnsemblGO_REF:0000107
NPAS3Bonobonucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
NPAS3Bonobonucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043

Molecular Function

  

PMID:22301074   PMID:30032202  



NPAS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01413,701,786 - 14,568,738 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11431,990,835 - 32,759,347 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1431,893,101 - 32,758,096 (+)Ensemblpanpan1.1panPan2
NPAS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381432,934,785 - 33,804,173 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1432,934,396 - 33,820,863 (+)EnsemblGRCh38hg38GRCh38
GRCh371433,408,085 - 34,273,379 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361432,478,200 - 33,340,702 (+)NCBINCBI36Build 36hg18NCBI36
Build 341432,478,273 - 33,340,066NCBI
Celera1413,273,962 - 14,138,956 (+)NCBICelera
Cytogenetic Map14q13.1NCBI
HuRef1413,641,962 - 14,390,327 (+)NCBIHuRef
CHM1_11433,407,064 - 34,271,980 (+)NCBICHM1_1
T2T-CHM13v2.01427,131,685 - 28,001,533 (+)NCBIT2T-CHM13v2.0
Npas3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391253,294,874 - 54,118,956 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1253,294,940 - 54,118,958 (+)EnsemblGRCm39 Ensembl
GRCm381253,248,026 - 54,072,173 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1253,248,677 - 54,072,175 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1253,248,157 - 54,072,175 (+)EnsemblGRCm38mm10GRCm38
MGSCv371254,349,664 - 55,173,162 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361254,170,303 - 54,990,700 (+)NCBIMGSCv36mm8
Celera1254,549,790 - 55,376,477 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1222.31NCBI
Npas3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8676,438,064 - 77,263,185 (+)NCBIGRCr8
mRatBN7.2670,702,773 - 71,527,928 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl670,703,170 - 71,524,884 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0674,081,995 - 74,913,025 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0683,635,089 - 84,459,466 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4674,192,110 - 74,209,762 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1674,075,148 - 74,329,176 (+)NCBI
Celera669,567,922 - 70,382,732 (+)NCBICelera
Cytogenetic Map6q23NCBI
Npas3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540927,137,667 - 27,975,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540927,134,610 - 27,975,282 (-)NCBIChiLan1.0ChiLan1.0
NPAS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1811,959,895 - 12,799,448 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha811,763,424 - 12,608,564 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0812,062,501 - 12,903,397 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl812,061,655 - 12,900,182 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1811,746,047 - 12,585,489 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0811,827,729 - 12,667,988 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0812,112,108 - 12,957,329 (+)NCBIUU_Cfam_GSD_1.0
Npas3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864043,803,562 - 44,639,066 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364947,310,005 - 8,143,610 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364947,965,156 - 8,144,244 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPAS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl765,928,075 - 66,800,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1765,924,986 - 66,800,820 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2770,862,116 - 70,974,873 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Npas3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248383,006,512 - 3,904,799 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248383,003,455 - 3,904,964 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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1 to 17 of 17 rows
RefSeq Transcripts XM_034937407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034937417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055097464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055097465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057299681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057299682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057299683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 17 of 17 rows

Ensembl Acc Id: ENSPPAT00000032411   ⟹   ENSPPAP00000009768
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1431,893,101 - 32,758,096 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000032420   ⟹   ENSPPAP00000009776
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1432,173,260 - 32,758,096 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000032425   ⟹   ENSPPAP00000009781
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1432,324,848 - 32,638,957 (+)Ensembl
RefSeq Acc Id: XM_034937407   ⟹   XP_034793298
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBI
Mhudiblu_PPA_v01413,701,786 - 14,567,006 (+)NCBI
RefSeq Acc Id: XM_034937408   ⟹   XP_034793299
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBI
Mhudiblu_PPA_v01413,701,786 - 14,567,006 (+)NCBI
RefSeq Acc Id: XM_034937409   ⟹   XP_034793300
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBI
Mhudiblu_PPA_v01413,701,786 - 14,567,006 (+)NCBI
RefSeq Acc Id: XM_034937410   ⟹   XP_034793301
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBI
Mhudiblu_PPA_v01413,701,786 - 14,567,006 (+)NCBI
RefSeq Acc Id: XM_034937411   ⟹   XP_034793302
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBI
Mhudiblu_PPA_v01413,701,786 - 14,567,006 (+)NCBI
RefSeq Acc Id: XM_034937412   ⟹   XP_034793303
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,258,809 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,475,312 - 34,338,452 (+)NCBI
Mhudiblu_PPA_v01413,705,808 - 14,568,738 (+)NCBI
RefSeq Acc Id: XM_034937413   ⟹   XP_034793304
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,258,809 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,475,312 - 34,338,452 (+)NCBI
Mhudiblu_PPA_v01413,705,808 - 14,568,738 (+)NCBI
RefSeq Acc Id: XM_034937415   ⟹   XP_034793306
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,258,809 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,475,312 - 34,338,452 (+)NCBI
Mhudiblu_PPA_v01413,705,808 - 14,568,738 (+)NCBI
RefSeq Acc Id: XM_055097464   ⟹   XP_054953439
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBI
RefSeq Acc Id: XM_055097465   ⟹   XP_054953440
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBI
RefSeq Acc Id: XM_057299681   ⟹   XP_057155664
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,258,809 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,475,312 - 34,338,452 (+)NCBI
RefSeq Acc Id: XM_057299682   ⟹   XP_057155665
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,258,809 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,475,312 - 34,338,452 (+)NCBI
RefSeq Acc Id: XM_057299683   ⟹   XP_057155666
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21534,258,809 - 35,121,949 (+)NCBI
NHGRI_mPanPan11433,475,312 - 34,338,452 (+)NCBI
1 to 5 of 16 rows
1 to 5 of 16 rows
RefSeq Acc Id: XP_034793298   ⟸   XM_034937407
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A1G7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793299   ⟸   XM_034937408
- Peptide Label: isoform X3
- UniProtKB: A0A2R9A1G7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793300   ⟸   XM_034937409
- Peptide Label: isoform X4
- UniProtKB: A0A2R9A1G7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793301   ⟸   XM_034937410
- Peptide Label: isoform X5
- UniProtKB: A0A2R9A1G7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034793302   ⟸   XM_034937411
- Peptide Label: isoform X7
- UniProtKB: A0A2R8ZXT8 (UniProtKB/TrEMBL)
bHLH   PAS



1 to 26 of 26 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000028096 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000032411.1 UniProtKB/TrEMBL
  ENSPPAT00000032420.1 UniProtKB/TrEMBL
  ENSPPAT00000032425.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
  PAS_fold_3 UniProtKB/TrEMBL
NCBI Gene NPAS3 ENTREZGENE
PANTHER HYPOXIA-INDUCIBLE FACTOR 1 ALPHA UniProtKB/TrEMBL
  NEURONAL PAS DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
Pfam PAS UniProtKB/TrEMBL
  PAS_3 UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
UniProt A0A2R8ZXT8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZXU5_PANPA UniProtKB/TrEMBL
  A0A2R9A1G7 ENTREZGENE, UniProtKB/TrEMBL
1 to 26 of 26 rows