Npas3 (neuronal PAS domain protein 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Npas3 (neuronal PAS domain protein 3) Heterocephalus glaber
Analyze
Symbol: Npas3
Name: neuronal PAS domain protein 3
RGD ID: 18923473
Description: ENCODES a protein that exhibits protein heterodimerization activity (ortholog); INVOLVED IN locomotory behavior (ortholog); maternal behavior (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); schizophrenia (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neuronal PAS domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248383,006,512 - 3,904,799 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248383,003,455 - 3,904,964 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (ISO)
nucleus  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Npas3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248383,006,512 - 3,904,799 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248383,003,455 - 3,904,964 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NPAS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381432,934,785 - 33,804,173 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1432,934,396 - 33,820,863 (+)EnsemblGRCh38hg38GRCh38
GRCh371433,408,085 - 34,273,379 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361432,478,200 - 33,340,702 (+)NCBINCBI36Build 36hg18NCBI36
Build 341432,478,273 - 33,340,066NCBI
Celera1413,273,962 - 14,138,956 (+)NCBICelera
Cytogenetic Map14q13.1NCBI
HuRef1413,641,962 - 14,390,327 (+)NCBIHuRef
CHM1_11433,407,064 - 34,271,980 (+)NCBICHM1_1
T2T-CHM13v2.01427,131,685 - 28,001,533 (+)NCBIT2T-CHM13v2.0
Npas3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391253,294,874 - 54,118,956 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1253,294,940 - 54,118,958 (+)EnsemblGRCm39 Ensembl
GRCm381253,248,026 - 54,072,173 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1253,248,677 - 54,072,175 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1253,248,157 - 54,072,175 (+)EnsemblGRCm38mm10GRCm38
MGSCv371254,349,664 - 55,173,162 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361254,170,303 - 54,990,700 (+)NCBIMGSCv36mm8
Celera1254,549,790 - 55,376,477 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1222.31NCBI
Npas3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8676,438,064 - 77,263,185 (+)NCBIGRCr8
mRatBN7.2670,702,773 - 71,527,928 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl670,703,170 - 71,524,884 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0674,081,995 - 74,913,025 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0683,635,089 - 84,459,466 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4674,192,110 - 74,209,762 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1674,075,148 - 74,329,176 (+)NCBI
Celera669,567,922 - 70,382,732 (+)NCBICelera
Cytogenetic Map6q23NCBI
Npas3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540927,137,667 - 27,975,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540927,134,610 - 27,975,282 (-)NCBIChiLan1.0ChiLan1.0
NPAS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21534,254,792 - 35,121,949 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11433,471,295 - 34,338,452 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01413,701,786 - 14,568,738 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11431,990,835 - 32,759,347 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1431,893,101 - 32,758,096 (+)Ensemblpanpan1.1panPan2
NPAS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1811,959,895 - 12,799,448 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha811,763,424 - 12,608,564 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0812,062,501 - 12,903,397 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl812,061,655 - 12,900,182 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1811,746,047 - 12,585,489 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0811,827,729 - 12,667,988 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0812,112,108 - 12,957,329 (+)NCBIUU_Cfam_GSD_1.0
Npas3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864043,803,562 - 44,639,066 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364947,310,005 - 8,143,610 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364947,965,156 - 8,144,244 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPAS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl765,928,075 - 66,800,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1765,924,986 - 66,800,820 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2770,862,116 - 70,974,873 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004867578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004867579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013066627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013066630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013066631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021246625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01086431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01086453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000000917   ⟹   ENSHGLP00000000876
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248383,006,512 - 3,904,799 (-)Ensembl
RefSeq Acc Id: XM_004867578   ⟹   XP_004867635
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248383,006,512 - 3,904,964 (-)NCBI
RefSeq Acc Id: XM_004867579   ⟹   XP_004867636
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248383,003,455 - 3,904,964 (-)NCBI
RefSeq Acc Id: XM_013066627   ⟹   XP_012922081
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248383,006,512 - 3,900,373 (-)NCBI
RefSeq Acc Id: XM_013066630   ⟹   XP_012922084
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248383,006,512 - 3,904,964 (-)NCBI
RefSeq Acc Id: XM_013066631   ⟹   XP_012922085
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248383,006,512 - 3,900,393 (-)NCBI
RefSeq Acc Id: XM_021246622   ⟹   XP_021102281
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248383,003,455 - 3,904,964 (-)NCBI
RefSeq Acc Id: XM_021246624   ⟹   XP_021102283
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248383,003,455 - 3,904,964 (-)NCBI
RefSeq Acc Id: XM_021246625   ⟹   XP_021102284
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248383,003,455 - 3,904,964 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004867636   ⟸   XM_004867579
- Peptide Label: isoform X5
- UniProtKB: G5BG42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102283   ⟸   XM_021246624
- Peptide Label: isoform X3
- UniProtKB: G5BG42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102281   ⟸   XM_021246622
- Peptide Label: isoform X1
- UniProtKB: G5BG42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102284   ⟸   XM_021246625
- Peptide Label: isoform X8
- UniProtKB: G5BG42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922084   ⟸   XM_013066630
- Peptide Label: isoform X4
- UniProtKB: G5BG42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004867635   ⟸   XM_004867578
- Peptide Label: isoform X2
- UniProtKB: G5BG42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922085   ⟸   XM_013066631
- Peptide Label: isoform X7
- UniProtKB: G5BG42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922081   ⟸   XM_013066627
- Peptide Label: isoform X6
- UniProtKB: G5BG42 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000000876   ⟸   ENSHGLT00000000917


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000723 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000000917 ENTREZGENE
Gene3D-CATH PAS domain UniProtKB/TrEMBL
InterPro PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold_3 UniProtKB/TrEMBL
NCBI Gene Npas3 ENTREZGENE
PANTHER HYPOXIA-INDUCIBLE FACTOR 1 ALPHA UniProtKB/TrEMBL
  NEURONAL PAS DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
Pfam PAS_3 UniProtKB/TrEMBL
PROSITE PAS UniProtKB/TrEMBL
SMART PAS UniProtKB/TrEMBL
Superfamily-SCOP PYP-like sensor domain (PAS domain) UniProtKB/TrEMBL
UniProt G5BG42 ENTREZGENE, UniProtKB/TrEMBL