SOHLH2 (spermatogenesis and oogenesis specific basic helix-loop-helix 2) - Rat Genome Database

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Gene: SOHLH2 (spermatogenesis and oogenesis specific basic helix-loop-helix 2) Pan paniscus
Analyze
Symbol: SOHLH2
Name: spermatogenesis and oogenesis specific basic helix-loop-helix 2
RGD ID: 11671217
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN cell differentiation (ortholog); oocyte differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC103783034; LOC103783035; spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2; spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21435,692,409 - 35,743,843 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11326,798,408 - 26,849,838 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01317,379,900 - 17,426,758 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11335,811,256 - 35,857,611 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1335,812,074 - 35,857,528 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SOHLH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21435,692,409 - 35,743,843 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11326,798,408 - 26,849,838 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01317,379,900 - 17,426,758 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11335,811,256 - 35,857,611 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1335,812,074 - 35,857,528 (-)Ensemblpanpan1.1panPan2
SOHLH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381336,168,217 - 36,214,556 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1336,168,217 - 36,214,588 (-)EnsemblGRCh38hg38GRCh38
GRCh371336,742,354 - 36,788,693 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361335,640,354 - 35,686,676 (-)NCBINCBI36Build 36hg18NCBI36
Celera1317,809,516 - 17,855,920 (-)NCBICelera
Cytogenetic Map13q13.3NCBI
HuRef1317,554,581 - 17,600,987 (-)NCBIHuRef
CHM1_11336,709,919 - 36,756,323 (-)NCBICHM1_1
T2T-CHM13v2.01335,387,717 - 35,434,075 (-)NCBIT2T-CHM13v2.0
Sohlh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39355,089,465 - 55,117,378 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl355,089,449 - 55,117,378 (+)EnsemblGRCm39 Ensembl
GRCm38355,182,044 - 55,209,957 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl355,182,028 - 55,209,957 (+)EnsemblGRCm38mm10GRCm38
MGSCv37354,985,966 - 55,013,879 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36355,269,973 - 55,297,879 (+)NCBIMGSCv36mm8
Celera354,899,830 - 54,927,744 (+)NCBICelera
Cytogenetic Map3CNCBI
cM Map326.53NCBI
Sohlh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82141,512,410 - 141,534,864 (+)NCBIGRCr8
mRatBN7.22139,362,246 - 139,384,700 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2139,362,246 - 139,384,699 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2145,937,104 - 145,959,408 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02144,048,536 - 144,070,836 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02138,680,966 - 138,703,265 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02144,591,755 - 144,614,065 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2144,591,755 - 144,614,064 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02164,007,688 - 164,029,998 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42144,406,048 - 144,428,502 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2133,845,930 - 133,868,318 (+)NCBICelera
Cytogenetic Map2q26NCBI
Sohlh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554319,884,173 - 9,942,826 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554319,874,783 - 9,952,044 (+)NCBIChiLan1.0ChiLan1.0
Sohlh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945165,559,534 - 165,610,877 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647230,335,290 - 30,392,621 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOHLH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1314,753,901 - 14,800,910 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl314,753,989 - 14,834,381 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605729,493,859 - 29,540,194 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sohlh2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247761,192,573 - 1,269,672 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247761,192,539 - 1,273,346 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000027834   ⟹   ENSPPAP00000006489
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1335,812,074 - 35,857,528 (-)Ensembl
RefSeq Acc Id: XM_024925304   ⟹   XP_024781072
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21435,692,409 - 35,743,843 (-)NCBI
NHGRI_mPanPan11326,798,408 - 26,849,838 (-)NCBI
Mhudiblu_PPA_v01317,379,900 - 17,426,758 (-)NCBI
PanPan1.11335,811,256 - 35,857,611 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_024781072 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABM54396 (Get FASTA)   NCBI Sequence Viewer  
  ABM54397 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000006489
  ENSPPAP00000006489.1
Reference Protein Sequences
RefSeq Acc Id: XP_024781072   ⟸   XM_024925304
- UniProtKB: A0A2R8ZUD7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000006489   ⟸   ENSPPAT00000027834
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000025183 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000027834.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  TCFL5/SOLH1/2 UniProtKB/TrEMBL
NCBI Gene LOC103783034 ENTREZGENE
PANTHER BHLH DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR-LIKE 5 PROTEIN UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A2R8ZUD7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 SOHLH2  spermatogenesis and oogenesis specific basic helix-loop-helix 2  LOC103783035  spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2-like  Data merged from RGD:11989534 737654 PROVISIONAL
2018-05-08 SOHLH2  spermatogenesis and oogenesis specific basic helix-loop-helix 2  LOC103783034  spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2  Symbol and/or name change 5135510 APPROVED