Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2606
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fgf10
Name: fibroblast growth factor 10
Acc ID: CHEBI:91091
Term: CHIR 99021
Definition: A member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively.
Chemical ID: MESH:C473711
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgf10multiple interactionsISOFGF10 (Homo sapiens)6480464CTD[Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of CD68 mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of CSF2 mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of HOPX mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of MUC1 protein; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of MUC5AC mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of NKX2-1 mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of PPARG mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of SFTPA mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of SFTPC mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of SOX9 mRNA; [Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of TTF1 proteinPMID:35267148
Go Back to source page   Continue to Ontology report