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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731002
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: CHEBI:8711
Term: quinacrine
Definition: A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.
Chemical ID: MESH:D011796
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3increases activityEXP 6480464CTDQuinacrine results in increased activity of CASP3 proteinPMID:28720477
CASP3increases cleavageEXP 6480464CTDQuinacrine results in increased cleavage of CASP3 proteinPMID:28867437
CASP3multiple interactionsEXP 6480464CTDGSK3B protein affects the reaction [Quinacrine results in increased activity of CASP3 protein]PMID:28720477
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