GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1b1 | increases expression | ISO | CYP1B1 (Homo sapiens) | 6480464 | CTD | indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 mRNA; indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein | PMID:17253728 PMID:27196671 PMID:35687267 | Cyp1b1 | multiple interactions | ISO | CYP1B1 (Homo sapiens) | 6480464 | CTD | 1-methyltryptophan inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein]; 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein]; epacadostat inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein]; U 0126 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 protein] | PMID:35687267 | | ||||||||||||||||||||||
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