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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3317
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pgr
Name: progesterone receptor
Acc ID: CHEBI:81525
Term: 2,3,3',4,4',5,5'-Heptachlorobiphenyl
Definition: A heptachlorobiphenyl that has formula C12H3Cl7.
Chemical ID: MESH:C034559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pgrmultiple interactionsISOPGR (Homo sapiens)6480464CTD2,2',3,3',4,4',5-heptachlorobiphenyl inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]PMID:26022396
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