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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2295251
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c52-ps
Name: cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene
Acc ID: CHEBI:77013
Term: beta-naphthoflavone
Definition: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
Chemical ID: MESH:D019324
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c52-psdecreases expressionISOCYP2C18 (Homo sapiens)6480464CTDbeta-Naphthoflavone results in decreased expression of CYP2C18 mRNAPMID:16985168
Cyp2c52-psmultiple interactionsISOCyp2c11 (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C11 proteinPMID:18164116 PMID:30842367
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