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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736773
Species: Mus musculus
RGD Object: Gene
Symbol: Slc1a2
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Acc ID: CHEBI:61080
Term: romidepsin
Definition: A cyclodepsipeptide consisting of the cyclic disulfide of (2Z)-2-aminobut-2-enoyl, L-valyl, (3S,4E)-3-hydroxy-7-sulfanylhept-4-enoyl, D-valyl and D-cysteinyl residues coupled in sequence and cyclised head-to tail.
Chemical ID: MESH:C087123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc1a2increases expressionISOSlc1a2 (Rattus norvegicus)6480464CTDromidepsin results in increased expression of SLC1A2 mRNAPMID:24469401
Slc1a2multiple interactionsISOSlc1a2 (Rattus norvegicus)6480464CTDromidepsin inhibits the reaction [Manganese results in decreased expression of SLC1A2 mRNA]PMID:24469401
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