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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735341
Species: Homo sapiens
RGD Object: Gene
Symbol: CDKN1A
Name: cyclin dependent kinase inhibitor 1A
Acc ID: CHEBI:52289
Term: wortmannin
Definition: A delta-lactone that has formula C23H24O8.
Chemical ID: MESH:C009687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDKN1Adecreases expressionEXP 6480464CTDwortmannin results in decreased expression of CDKN1A proteinPMID:22290291
CDKN1Amultiple interactionsEXP 6480464CTDwortmannin inhibits the reaction [Aspirin results in increased expression of CDKN1A protein]; wortmannin inhibits the reaction [docetaxel results in increased expression of CDKN1A protein]PMID:20878124 PMID:21617849
CDKN1Aincreases expressionISOCdkn1a (Mus musculus)6480464CTDwortmannin results in increased expression of CDKN1A proteinPMID:15695173 PMID:17129604
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