GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL6 | multiple interactions | EXP | | 6480464 | CTD | [4'-hydroxywogonin co-treated with Wortmannin] inhibits the reaction [IL6 protein results in increased expression of and results in increased secretion of VEGFA protein]; [4'-hydroxywogonin co-treated with Wortmannin] inhibits the reaction [IL6 protein results in increased expression of VEGFA mRNA]; Wortmannin inhibits the reaction [IL6 protein results in increased expression of and results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [IL6 protein results in increased expression of VEGFA mRNA] | PMID:30217479 | IL6 | multiple interactions | ISO | Il6 (Mus musculus) | 6480464 | CTD | wortmannin inhibits the reaction [di-n-butyltin results in increased expression of IL6 mRNA]; wortmannin inhibits the reaction [di-n-butyltin results in increased expression of IL6 protein] | PMID:24631921 | IL6 | multiple interactions | ISO | Il6 (Rattus norvegicus) | 6480464 | CTD | wortmannin inhibits the reaction [resveratrol results in decreased activity of IL6 protein] | PMID:20117814 | |
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