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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10823
Species: Mus musculus
RGD Object: Gene
Symbol: Jak2
Name: Janus kinase 2
Acc ID: CHEBI:5169
Term: fraxetin
Definition: A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups.
Chemical ID: MESH:C105671
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Jak2decreases phosphorylationISOJAK2 (Homo sapiens)125097526RGDFraxetin decreases phosphorylation of JAK2 protein in colorectum 
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