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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735787
Species: Homo sapiens
RGD Object: Gene
Symbol: APOB
Name: apolipoprotein B
Acc ID: CHEBI:50686
Term: atorvastatin calcium
Definition: An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio.
Chemical ID: MESH:D000069059
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
APOBdecreases expressionEXP 6480464CTDAtorvastatin results in decreased expression of APOB proteinPMID:12172771 PMID:12633795 PMID:18702965
APOBdecreases secretionEXP 6480464CTDAtorvastatin results in decreased secretion of APOB proteinPMID:10357840 PMID:11728391 PMID:9512650
APOBmultiple interactionsEXP 6480464CTDAtorvastatin results in decreased expression of and results in decreased secretion of APOB proteinPMID:12612140
APOBmultiple interactionsISOApob (Rattus norvegicus)6480464CTDAtorvastatin inhibits the reaction [Fructose results in increased expression of APOB protein]PMID:12065722
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