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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70502
Species: Homo sapiens
RGD Object: Gene
Symbol: TP53
Name: tumor protein p53
Acc ID: CHEBI:50686
Term: atorvastatin calcium
Definition: An organic calcium salt composed of calcium cations and atorvastatin anions in a 1:2 ratio.
Chemical ID: MESH:D000069059
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TP53increases expressionEXP 6480464CTDAtorvastatin results in increased expression of TP53 proteinPMID:29630879
TP53multiple interactionsISOTrp53 (Mus musculus)6480464CTDAtorvastatin inhibits the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TRP53 protein]PMID:37121058
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