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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708541
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Acc ID: CHEBI:47381
Term: diclofenac
Definition: A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Chemical ID: MESH:D004008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt2b1increases glucuronidationISOUGT2B17 (Homo sapiens)6480464CTDUGT2B17 protein results in increased glucuronidation of DiclofenacPMID:15843492 PMID:22265884
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