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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558069
Species: Mus musculus
RGD Object: Gene
Symbol: Hspa1a
Name: heat shock protein 1A
Acc ID: CHEBI:47381
Term: diclofenac
Definition: A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.
Chemical ID: MESH:D004008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspa1aaffects expressionEXP 6480464CTDDiclofenac affects the expression of HSPA1A mRNAPMID:26934552
Hspa1aincreases expressionEXP 6480464CTDDiclofenac results in increased expression of HSPA1A mRNAPMID:26934552
Hspa1aincreases expressionISOHspa1a (Rattus norvegicus)6480464CTDDiclofenac results in increased expression of HSPA1A mRNAPMID:19022234 PMID:25014874
Hspa1amultiple interactionsISOHspa1a (Rattus norvegicus)6480464CTDDiclofenac inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HSPA1A mRNA]PMID:23939143
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