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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10576
Species: Mus musculus
RGD Object: Gene
Symbol: Fga
Name: fibrinogen alpha chain
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fgaaffects expressionEXP 6480464CTDperfluorooctanoic acid affects the expression of FGA mRNAPMID:19429403
Fgadecreases expressionEXP 6480464CTDperfluorooctanoic acid results in decreased expression of FGA mRNAPMID:18467677
Fgamultiple interactionsEXP 6480464CTDPPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of FGA mRNA]PMID:18467677
Fgadecreases expressionISOFga (Rattus norvegicus)6480464CTDperfluorooctanoic acid results in decreased expression of FGA mRNAPMID:19162173
Fgadecreases expressionISOFGA (Homo sapiens)6480464CTDperfluorooctanoic acid results in decreased expression of FGA mRNA; perfluorooctanoic acid results in decreased expression of FGA proteinPMID:25868421 PMID:26879310
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