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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tp53
Name: tumor protein p53
Acc ID: CHEBI:35170
Term: vanadium(0)
Definition: An elemental vanadium that has formula V.
Chemical ID: MESH:D014639
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tp53multiple interactionsEXP 6480464CTDVanadium inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of TP53 protein]; Vanadium promotes the reaction [2-Acetylaminofluorene results in increased expression of TP53 protein]PMID:15565650 PMID:18155637
Tp53increases activityISOTP53 (Homo sapiens)6480464CTDVanadium results in increased activity of TP53 proteinPMID:19000753
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