GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AR | affects binding | EXP | | 6480464 | CTD | mibolerone binds to AR protein | PMID:12676605 PMID:15253041 PMID:17606915 | AR | affects localization | EXP | | 6480464 | CTD | mibolerone affects the localization of AR protein | PMID:15509168 PMID:15661808 | AR | increases activity | EXP | | 6480464 | CTD | mibolerone results in increased activity of AR protein | PMID:8798622 | AR | increases expression | EXP | | 6480464 | CTD | mibolerone results in increased expression of AR protein | PMID:15661808 PMID:17075824 PMID:20148354 PMID:20692244 | AR | increases localization | EXP | | 6480464 | CTD | mibolerone results in increased localization of AR protein | PMID:15466214 | AR | increases phosphorylation | EXP | | 6480464 | CTD | mibolerone results in increased phosphorylation of AR protein | PMID:15661808 | AR | multiple interactions | EXP | | 6480464 | CTD | [mibolerone binds to and results in increased activity of AR protein] inhibits the reaction [ETS1 protein results in increased expression of MMP1 mRNA]; [mibolerone binds to and results in increased activity of AR protein] inhibits the reaction [ETV4 protein results in increased expression of MMP1 mRNA]; [mibolerone binds to and results in increased activity of AR protein] inhibits the reaction [ETV5 protein results in increased expression of MMP1 mRNA]; [Quercetin co-treated with mibolerone] promotes the reaction [AR protein binds to JUN protein]; [Quercetin co-treated with mibolerone] promotes the reaction [SP1 protein binds to JUN protein binds to AR protein]; mibolerone inhibits the reaction [bicalutamide results in increased expression of AR protein]; mibolerone promotes the reaction [SP1 protein binds to AR protein]; nilutamide inhibits the reaction [mibolerone affects the localization of AR protein]; pyrazolanthrone affects the reaction [Quercetin inhibits the reaction [mibolerone results in increased expression of AR protein]]; Quercetin affects the reaction [mibolerone affects the localization of AR protein]; Quercetin inhibits the reaction [mibolerone results in increased expression of AR protein]; Quercetin inhibits the reaction [mibolerone results in increased phosphorylation of AR protein]; Quercetin promotes the reaction [mibolerone promotes the reaction [SP1 protein binds to AR protein]]; retigeric acid B inhibits the reaction [mibolerone results in increased expression of AR protein] | PMID:15509168 PMID:15661808 PMID:17723170 PMID:20148354 PMID:20692244 PMID:8798622 | AR | affects binding | ISO | Ar (Rattus norvegicus) | 6480464 | CTD | mibolerone binds to AR protein | PMID:14565775 PMID:18644453 | AR | multiple interactions | ISO | Ar (Mus musculus) | 6480464 | CTD | EGF protein promotes the reaction [mibolerone binds to AR protein] | PMID:8912815 | | ||||||||||||||||||||||
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