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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2295251
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c52-ps
Name: cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene
Acc ID: CHEBI:3441
Term: carvedilol
Definition: A member of the class of carbazoles that is an adrenergic antagonist with non-selective beta- and alpha-1 receptor blocking properties which helps in the management of congestive heart failure.
Chemical ID: MESH:C043211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c52-psincreases metabolic processingISOCyp2c11 (Rattus norvegicus)6480464CTDCYP2C11 protein results in increased metabolism of carvedilolPMID:29415952
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