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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621752
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lnpep
Name: leucyl and cystinyl aminopeptidase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lnpepdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of LNPEP mRNAPMID:25181051 PMID:34947998
Lnpepdecreases expressionISOLNPEP (Homo sapiens)6480464CTDbisphenol A results in decreased expression of LNPEP proteinPMID:31675489
Lnpepdecreases methylationISOLNPEP (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of LNPEP genePMID:31601247
Lnpepincreases expressionISOLNPEP (Homo sapiens)6480464CTDbisphenol A results in increased expression of LNPEP proteinPMID:34186270
Lnpepincreases expressionISOLnpep (Mus musculus)6480464CTDbisphenol A results in increased expression of LNPEP mRNAPMID:25594700
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