GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atr | affects expression | ISO | Atr (Mus musculus) | 6480464 | CTD | chromium hexavalent ion affects the expression of ATR mRNA | PMID:28472532 | Atr | increases activity | ISO | ATR (Homo sapiens) | 6480464 | CTD | chromium hexavalent ion results in increased activity of ATR protein | PMID:16876463 | Atr | multiple interactions | ISO | ATR (Homo sapiens) | 6480464 | CTD | ATR protein affects the reaction [chromium hexavalent ion results in increased phosphorylation of H2AX protein]; ATR protein affects the reaction [chromium hexavalent ion results in increased ubiquitination of H2AX protein]; chromium hexavalent ion promotes the reaction [ATR protein results in increased phosphorylation of SMC1A protein]; RAD17 protein affects the reaction [chromium hexavalent ion promotes the reaction [ATR protein results in increased phosphorylation of SMC1A protein]] | PMID:16876463 PMID:25288669 | Atr | multiple interactions | ISO | Atr (Mus musculus) | 6480464 | CTD | ATR protein affects the reaction [chromium hexavalent ion results in increased phosphorylation of H2AX protein]; ATR protein affects the reaction [chromium hexavalent ion results in increased ubiquitination of H2AX protein] | PMID:25288669 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |