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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70487
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ctnnb1
Name: catenin beta 1
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ctnnb1multiple interactionsEXP 6480464CTDpirinixic acid inhibits the reaction [APP protein results in decreased expression of CTNNB1 protein]; pirinixic acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of CTNNB1 protein]; pirinixic acid inhibits the reaction [Hydrogen Peroxide results in decreased stability of CTNNB1 protein]PMID:16204253
Ctnnb1decreases expressionISOCtnnb1 (Mus musculus)6480464CTDpirinixic acid results in decreased expression of CTNNB1 mRNAPMID:18445702
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