Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	735618
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	NOS3
Name:	nitric oxide synthase 3

Acc ID:	CHEBI:31654
Term:	gliclazide
Definition:	A N-sulfonylurea that has formula C15H21N3O3S.
Chemical ID:	MESH:D005907

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
NOS3	increases expression	ISO	Nos3 (Rattus norvegicus)	6480464	CTD	Gliclazide results in increased expression of NOS3 protein	PMID:14871415

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.