GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Insr | increases phosphorylation | EXP | | 6480464 | CTD | Zinc results in increased phosphorylation of INSR protein | PMID:15516700 | Insr | multiple interactions | EXP | | 6480464 | CTD | Chromium promotes the reaction [Zinc results in increased phosphorylation of INSR protein]; Zinc promotes the reaction [Chromium results in increased phosphorylation of INSR protein] | PMID:15516700 | Insr | affects expression | ISO | Insr (Rattus norvegicus) | 6480464 | CTD | Zinc affects the expression of INSR mRNA | PMID:16413754 | Insr | decreases expression | ISO | Insr (Rattus norvegicus) | 6480464 | CTD | Zinc deficiency results in decreased expression of INSR mRNA; Zinc deficiency results in decreased expression of INSR protein | PMID:21893222 | Insr | multiple interactions | ISO | Insr (Rattus norvegicus) | 6480464 | CTD | [Zinc co-treated with INS1 protein] results in increased phosphorylation of INSR protein | PMID:1321133 | |
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