GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcb1a | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] | PMID:10636889 PMID:18474546 | Abcb1a | multiple interactions | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]; Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA] | PMID:22914566 PMID:23867903 PMID:25824409 | | ||||||||||||||||||||||
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