GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MT2A | decreases expression | EXP | | 6480464 | CTD | Rotenone results in decreased expression of MT2A mRNA | PMID:36586010 | MT2A | increases expression | EXP | | 6480464 | CTD | Rotenone results in increased expression of MT2A mRNA | PMID:16402917 PMID:32870474 | MT2A | multiple interactions | EXP | | 6480464 | CTD | MT2A protein inhibits the reaction [Rotenone results in increased abundance of Reactive Oxygen Species]; MT2A protein inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; MT2A protein inhibits the reaction [Rotenone results in increased activity of CASP7 protein] | PMID:16402917 | MT2A | affects expression | ISO | Mt2A (Rattus norvegicus) | 6480464 | CTD | Rotenone affects the expression of MT2A mRNA | PMID:28374803 | MT2A | increases expression | ISO | Mt2A (Rattus norvegicus) | 6480464 | CTD | Rotenone results in increased expression of MT2 mRNA | PMID:19818760 | MT2A | increases expression | ISO | Mt2 (Mus musculus) | 6480464 | CTD | Rotenone results in increased expression of MT2 mRNA | PMID:23186747 | MT2A | multiple interactions | ISO | Mt2A (Rattus norvegicus) | 6480464 | CTD | GPX4 protein inhibits the reaction [Rotenone results in increased expression of MT2 mRNA] | PMID:19818760 | |
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