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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2300155
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pnkd
Name: PNKD metallo-beta-lactamase domain containing
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pnkddecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PNKD mRNAPMID:32109520
Pnkdincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PNKD mRNAPMID:34747641
Pnkdaffects expressionISOPnkd (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PNKD mRNAPMID:21570461 PMID:28922406
Pnkddecreases expressionISOPnkd (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PNKD mRNAPMID:19465110 PMID:19770486 PMID:26290441
Pnkdincreases expressionISOPnkd (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PNKD mRNAPMID:29935226
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