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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734432
Species: Mus musculus
RGD Object: Gene
Symbol: Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Acc ID: CHEBI:27882
Term: (S)-colchicine
Definition: A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions.
Chemical ID: MESH:D003078
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2multiple interactionsEXP 6480464CTDColchicine inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 mRNA]PMID:37573684
Nfe2l2multiple interactionsISONFE2L2 (Homo sapiens)6480464CTD[dihydroactinidiolide co-treated with Colchicine] results in increased expression of NFE2L2 mRNAPMID:33617922
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