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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68335
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Por
Name: cytochrome p450 oxidoreductase
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Poraffects expressionEXP 6480464CTDresveratrol affects the expression of POR mRNAPMID:15748624
Porincreases expressionEXP 6480464CTDresveratrol results in increased expression of POR mRNAPMID:25905778
Porincreases expressionISOPor (Mus musculus)6480464CTDresveratrol results in increased expression of POR proteinPMID:25505154
Pormultiple interactionsISOPor (Mus musculus)6480464CTDresveratrol inhibits the reaction [POR protein affects the reaction [Benzo(a)pyrene results in increased chemical synthesis of benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA]]PMID:28111842
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