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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61928
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hif1a
Name: hypoxia inducible factor 1 subunit alpha
Acc ID: CHEBI:17703
Term: 26-hydroxycholesterol
Definition: An oxysterol that is cholesterol substituted at position 26 by a hydroxy group.
Chemical ID: MESH:C076996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hif1aincreases expressionISOHIF1A (Homo sapiens)6480464CTD27-hydroxycholesterol results in increased expression of HIF1A proteinPMID:27856279 PMID:33880675
Hif1amultiple interactionsISOHIF1A (Homo sapiens)6480464CTDHSPA9 protein promotes the reaction [27-hydroxycholesterol results in increased expression of HIF1A protein]PMID:33880675
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