GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GRIN1 | decreases activity | EXP | | 6480464 | CTD | Dizocilpine Maleate results in decreased activity of GRIN1 protein | PMID:19788891 | GRIN1 | multiple interactions | EXP | | 6480464 | CTD | [GRIN1 protein co-treated with GRIN2A protein] results in increased susceptibility to Dizocilpine Maleate; [GRIN1 protein co-treated with GRIN2B protein] results in increased susceptibility to Dizocilpine Maleate; Dizocilpine Maleate inhibits the reaction [[GRIN1 protein co-treated with GRIN2A protein] results in increased susceptibility to Excitatory Amino Acid Agonists] | PMID:19224577 | GRIN1 | affects binding | ISO | Grin1 (Rattus norvegicus) | 6480464 | CTD | Dizocilpine Maleate binds to GRIN1 protein | PMID:31202911 | GRIN1 | increases expression | ISO | Grin1 (Rattus norvegicus) | 6480464 | CTD | Dizocilpine Maleate results in increased expression of GRIN1 mRNA | PMID:25937004 | GRIN1 | multiple interactions | ISO | Grin1 (Rattus norvegicus) | 6480464 | CTD | Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN1 protein]; Dizocilpine Maleate inhibits the reaction [Folic Acid deficiency results in increased expression of GRIN1 protein]; Dizocilpine Maleate promotes the reaction [GRIN1 protein binds to SRC protein] | PMID:11249956 PMID:11801363 PMID:20406136 | | ||||||||||||||||||||||
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