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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731027
Species: Homo sapiens
RGD Object: Gene
Symbol: BDNF
Name: brain derived neurotrophic factor
Acc ID: CHEBI:176788
Term: dizocilpine maleate
Definition: A maleate salt obtained by reaction of dizocilpine with one equivalent of maleic acid.
Chemical ID: MESH:D016291
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BDNFaffects expressionISOBdnf (Rattus norvegicus)6480464CTDDizocilpine Maleate affects the expression of BDNF mRNAPMID:8405262
BDNFdecreases expressionISOBdnf (Rattus norvegicus)6480464CTDDizocilpine Maleate results in decreased expression of BDNF mRNAPMID:8247360
BDNFmultiple interactionsISOBdnf (Rattus norvegicus)6480464CTDDizocilpine Maleate inhibits the reaction [Pilocarpine results in increased expression of and results in increased localization of BDNF mRNA]; Pentobarbital inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]; Scopolamine inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]PMID:15282290 PMID:8405262
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