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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68494
Species: Mus musculus
RGD Object: Gene
Symbol: Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr5a1multiple interactionsEXP 6480464CTD[NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased abundance of TestosteronePMID:21610156
Nr5a1increases expressionISONr5a1 (Rattus norvegicus)6480464CTDTestosterone deficiency results in increased expression of NR5A1 mRNAPMID:8940405
Nr5a1multiple interactionsISONr5a1 (Rattus norvegicus)6480464CTDTestosterone inhibits the reaction [Testosterone deficiency results in increased expression of NR5A1 mRNA]PMID:8940405
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