Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68516
Species: Mus musculus
RGD Object: Gene
Symbol: Lrat
Name: lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
Acc ID: CHEBI:17336
Term: all-trans-retinol
Definition: A retinol in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lratdecreases expressionEXP 6480464CTDVitamin A results in decreased expression of LRAT mRNAPMID:30944279
Lratincreases expressionEXP 6480464CTDVitamin A results in increased expression of LRAT mRNAPMID:16292751
Lratmultiple interactionsEXP 6480464CTD[Vitamin A co-treated with Tetrachlorodibenzodioxin] results in increased expression of LRAT mRNA; Tetrachlorodibenzodioxin inhibits the reaction [Vitamin A results in increased expression of LRAT mRNA]PMID:16292751
Lrataffects expressionISOLrat (Rattus norvegicus)6480464CTDVitamin A affects the expression of LRAT mRNAPMID:12576510
Lratmultiple interactionsISOLRAT (Homo sapiens)6480464CTD[STRA6 protein co-treated with LRAT protein] results in increased uptake of Vitamin APMID:18316031
Go Back to source page   Continue to Ontology report